Pancreas Flashcards
the pancreas is what type or organ within where?
Retroperitoneal within anterior para renal space
Where is the pancreas located?
Posterior to the lesser sac
What is the AP dimension for the pancreas head?
3.5 cm or less
What is the AP dimension for the pancreas neck?
1-2.5 cm or less
What is the AP dimension for the pancreas body?
2.5 cm or less
What is the AP dimension for the pancreas tail?
2-2.5 cm or less
The uncinate process is part of what area of the pancreas?
Head
What do acini cells do?
Secrete digestive enzymes
What part of the pancreas is located medial to the C-loop of duodenum, anterior to the IVC, and inferior to the caudate liver lobe?
Head of Pancreas
What part of the pancreas is directly anterior to SMV or portalsplenic confluence?
Pancreas neck
What part of the pancreas is located posterior to portions of the stomach, duodenum, and left liver lobe?
Body of pancreas
What part of the pancreas is anterior and medial to left kidney, posterior to stomach, medial to spleen?
Pancreas tail
The main pancreatic duct is also known as?
Duct of wirsung
What two arteries supply the pancreas?
Splenic & pancreaticoduodenal
What are the enzymes of exocrine?
Acinar, lipase, trypsinogen and chymotrypsinogen, and amylase
Which enzyme secretes digestive enzymes?
Acinar
Which enzyme breaks down fat?
Lipase
Which enzymes are preproteolytic enzymes that break down proteins to amino acids?
Trypsinogen and Chymotrypsinogen
Which enzyme breaks down complex carbohydrates?
Amylase
How much fluid per day can the pancreas secrete?
1500 mL
What is exocrine?
Secretes enzymes into a duct
What is endocrine?
Hormones secrete into blood/tissues
What do the cells of the islets of Langerhans do?
Alpha cells secrete glucagon, Beta cells secrete insulin, Delta cells secrete somatostatin
In amylase, elevated levels are associated with?
Pancreatic diseases, biliary, bowel obstruction, and peptic ulcer
In amylase, decreased levels are associated with?
Permanent damage of the pancreas, hepatitis, and liver cirrhosis
Which lab value indicates acute pancreatitis when 2x the normal level?
Amylase
Which lab value has elevated lipase that may indicate acute pancreatitis or pancreatic carcinoma?
Lipase
Which lab value has total serum bilirubin values increased when pancreatic head obstructs the CBD?
Bilirubin and liver
Which lab value may indicate glucose metabolic disorder?
Elevated or decreased glucose
What is an annular pancreas?
Congenital anomaly
What are possible indications for an ultrasound of the pancreas?
Epigastric pain, Abdominal pain, Abdominal distension, Jaundice
What does patient prep involve for a pancreas ultrasound exam?
NPO 8-12 HOURS PRIOR TO EXAM
What are the most common causes of acute pancreatitis?
EDEMATOUS FORM (MOST COMMON), NECROTIZING FORM
What is a pancreatic pseudocyst?
A collection of fluid that resulted from an inflammatory process
What is a phlegmon?
An inflammatory process that spreads along fascial pathways
Why is a case of hemorrhagic pancreatitis so dangerous?
Fast of acute pancreatitis with rupture of pancreatic vessels resulting in hemorrhage
What disorder is an inherited disorder of the exocrine glands causing viscous secretion and dysfunction of the pancreas exocrine function?
Cystic fibrosis
This is the ultrasound appearance of : Pancreas appears hyperechoic, and decreased size of pancreas
Cystic fibrosis
What is a pancreatic cyst caused by?
Ductal obstruction
This is the ultrasound appearance of : Homogeneous, mid gray to medium gray echoes, equal to or more echogenic than liver, becomes more echogenic with age, and has a smooth contour
Normal pancreas
What should you do if you cannot visualize the pancreas?
Identify where you know the anatomy is and write down why you couldn’t scan it
What can the posterior wall of the stomach appear to be?
Duct of wirsung
How much water should a patient drink through a straw?
32 ml – 300 ml
Pancreatic cysts may be associated with cysts in which other organs?
Kidney & liver
These are the complications of : Pseudocyst formation, phlegmon, abscess, hemorrhage, and duodenal obstruction
Acute pancreatitis
What is the most common cause of acute pancreatitis?
Biliary tract disease & excessive alcohol intake
These are the signs and symptoms of : Constant epigastric and back pain, weight loss, steatorrhea, and diabetes mellitus
Chronic pancreatitis
These are the signs and symptoms of : Severe epigastric pain which radiates to back, nausea and vomiting, malaise, abdominal distention, fever, jaundice, and history of gallstones and alcohol abuse
Acute pancreatitis
These are the signs and symptoms of: Weight loss, chronic abdominal pain, back pain, painless jaundice, palpable abdominal mass, anorexia, nausea, vomiting, and malaise
Pancreatic carcinoma
This is the ultrasound appearance of: Most common in pancreatic head, hypoechoic mass, poorly defined, usually greater than 2cm, Courvoisier sign, liver mets, and ascites
Pancreatic carcinoma
What are the risk factors for pancreatic carcinoma?
More than 90% of all malignant pancreatic tumors, Blacks more than whites, Males more than females, Diet high in fat; low in fruits & vegetables, Increase with smoking, Chronic pancreatitis, Age; more common after 60 years, 4th most common cause of cancer-related mortality after lung, breast, and colon cancers
What is Courvoisier sign and what is it associated with?
Where a patient presents with painless jaundice and a palpable, enlarged gallbladder, typically associated with a malignant obstruction of the bile duct, most commonly caused by pancreatic cancer.
Describe the different types of acini cell tumors.
Adenocarcinoma – pancreatic carcinoma, Serous cystadenoma, Mucinous cystadenoma/cystadenocarcinoma
What are the different types of islet cell tumors?
Insulinoma, gastrinoma, and glucagonoma
Which islet cell tumor is most common?
Insulinoma (B cell)
Which islet cell is the 2nd most common?
Gastrinoma (G cell)
Which islet cell is usually benign (90-95%)?
Insulinoma
Which islet cell is rare?
Glucagonoma
Which islet cell produces Zollinger-Ellison syndrome?
Gastrinoma
What is a benign tumor, but can become malignant, common in women, and commonly found on pancreas body/tail?
Mucinous cystadenoma
What is a benign tumor, common in women, and commonly found on pancreas head?
Serous cystadenoma
What are the two functions of the pancreas?
Endocrine and exocrine
Which lab values would be important for pancreatitis?
Serum amylase and lipase levels