Pancreas Flashcards
Pseudocyst fluid analysis
High amylase, low CEA
Serous cystadenoma fluid analysis
Low amylase, low CEA
Mucinous cystic neoplasm fluid analysis
Low amylase, high CEA
IPMN fluid analysis
high amylase, high CEA
Mucinous cystic neoplasms
Body and tail, high mucin and CEA but low amylase; high malignant potential means resection with spleen preserving distal panc
Serous cystic neoplasms
Even distribution, Multiple small cysts separated by internal separations with central starburst calcifications; no mucin, CEA or amylase
IPMN
Mostly head, high mucin, CEA and amylase, Poorly demarcated, lobulated, polycystic mass with dilation of main or branch ducts
Annular pancreas
MC with Down’s, atresias (esophageal and duodenal), and imperforate anus, classic “double bubble” sign on x-ray, surgical bypass with duodenoduodenostomy, gastrojejunostomy, or duodenojejunostomy not resection
Primary pancreatic lymphoma
Large poorly enhancing homogenous mass with peripancreatic lymphadenopathy; elevated serum lactate dehydrogenase (LDH), elevated beta-2 microglobulin level, and a normal serum CA 19–9; B symptoms; chemo with R-CHOP
Unresectable for Whipple
Pancreatic cancer is considered unresectable with any metastases, extension into the hepatoduodenal ligament, involvement of major arterial structures, or involvement of nodal or neural structures around the celiac or superior mesenteric arteries. Isolated involvement of the superior mesenteric vein or portal vein can be resected in selected patients.
Autoimmune pancreatitis
diffusely enlarged hypodense pancreas or a focal mass that may be mistaken for pancreatic malignancy; Elevated IgG4 level; biopsy is indicated to rule out malignancy
Pancreatic ductal adenocarcinoma
infiltrate vascular, lymphatic, and perineural spaces; mets to LN and liver
Post-op pancreatic fistula
NPO, TPN, octreotide, MRCP for anatomy of leak
Whipple outcomes
There is no significant difference between pylorus-preserving pancreaticoduodenectomy and the classic Whipple operation in terms of either relative ease of performance or short- or long-term outcome (including survival).
Steps of Whipple
Determine if candidate
Open lesser sac and dissect inferior pancreas/SMV
Kocher and Cattell-Braash
Portal dissection and chole
Tunnel
Divide stomach
Divide pancreas
Divide jejunum
Reconstruct