Pam's Disease Through leprosy Flashcards
What disease(s) is/are associated with alpha virus?
Chik
What disease(s) is/are associated with flavivirus?
Zika
Dengue
Yellow Fever
What disease(s) is/are associated with filovirus?
Ebola
What disease(s) is/are associated with lyssavirus?
Rabies
What disease(s) is/are associated with Coronovirus?
MERS
SARS
What disease(s) is/are associated with
Vibrio Cholorarae
What disease(s) is/are associated with Treponema palladium and subspecies pertenue?
Yaws
What disease(s) is/are associated with francisella tularensis
Tularemia
What disease(s) is/are associated with mycobacterium leprae?
Leprosy
What disease(s) is/are associated with Trypanosoma Brucei?
Trympanosomiasis
What What disease(s) is/are associated with Rhodesiense and Gambienses?
African Sleeping Sickness
What disease(s) is/are associated with trypanosoma Cruzi?
trympanosomiasis
What disease(s) is/are associated with Triatomine?
Chagas
What disease(s) is/are associated with Taenia solium?
cysticercosis
What disease(s) is/are associated with onchocerca volvulus?
oncherocerclasis
CHIKUNGUNYA:
Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Transmission - alpha virus from Aedes eygypti and Aedes albopictus
Incubation- 3-7 days
Communicable period - as long as virus persists
Important S/S - ACUTE fever & SEVERE BILAT POLY ARTHRALGIA
Labs - PCR w/in 7 days, IGM/IGG after 4 days
Treatment- supportive/APAP/h2o/rest - self resolve
Mortaility - rare
ZIKA
Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Transmission - flavivirus Egypti & Albopictus & secondary transmission
Incubation - 2-14 days
Communicable period- avoid sex for 8 weeks post exposure. Post symptoms women- 8wk, men 6 mo and avoid pregnancy for 2 years
Important S/S - maculopap rash, conjunctivitis, small joint arthritis microcephaly and high risk of EBV
Other s/s
Labs- microcephaly at US 28-33 wks
Treatment- supportive, APAP- avoid NSAIDS r/o dengue
Mortaility- self resolve within 2-7days unless congenital passed on. LIFE LONG IMMUNITY
DENGUE
Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location- tropics and subtropics
Transmission- Flavivirus FEMALE -AEDES EGYPTI
Incubation- 4-10 days
Communicable period- 4-12days
Important S/S - Dengue fever >104 SEVERE RETRO ORBITAL PAIN
Other s/s - ….after 3 days the temp drops and symptoms get worse = hemorrhagic dengue
Labs- platelets <100k, diagnose clinically
Treatment- supportive, maintain BP
DF- oral hydration
DHF- isotonic IV fluids
Mortaility - if progressed to DHF death within 4 days
EBOLA
Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location - AFRICA
Transmission- Filovirus - 5 viruses - fruit bats and direct contact with MM/broken skin
Incubation- 8-10
Communicable period- up to 9 mo in semen
Important S/S- Sudden fever >101.5, severe HA, myalgia/weakness, fluid loss v/d
Other s/s - RASH, impaired renal/liver, high LFTs
Labs- Within 3 days ELISA/PCR Confirm virus in deceased
Treatment- supportive/isolation/ZMAPP antibodies
Mortaility- 90% spreads very quickly
Yellow Fever
Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location- Tropical Africa & Latin America
Transmission- Flavivirus Aedes and Haeomogus via bite monkeys and humans
Incubation- 3-6 days
Communicable period
Important S/S- chills/rigor/prominant back pain
FAGETS SIGN- decreasing HR with INCREASING TEMP
Other s/s- within 24 they appear more toxic, higher fever, jaundice bleeding diarrhea
Labs- IGM persists for 4 years
Treatment- Vaccine very effective
Mortaility- 50% in second phase(after24 hrs)
RABIES Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location - worldwide except Hawaii
Transmission- Lyssavirus from mammal saliva
Incubation- 1-3 mos
Communicable period
Important S/S- paresthesia at sight/hydrophobia/neuro symptoms
Other s/s- negative if it ever starts to get better or lasts longer than 2 weeks
Labs
Treatment- IMMEDIATE WOUND CLEANING! IMMEDIATE VACCINES
Mortaility- 100% witihin 10 days
MERS Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location- Arabian peninsula Transmission- Coronovirus - Camels and Bats Incubation- 5 days Communicable period Important S/S- URI with high risk location Other s/s PATCHY OPACITIES ON XRAY Labs- lung culture Treatment- vent, isolate and quarantine Mortaility - 30% around day 12
SARS Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location- China/Hong Kong Transmission- Coronavirus/Bats? Incubation- 2-7 days Communicable period - after 2nd week of illness Important S/S- Sever lower resp. illness in correct setting Other s/s Labs- PCR ASAP FROM AT LEAST 2 SITES Treatment- vent Mortaility
Cholera Endemic Location Transmission Incubation Important S/S Other s/s Treatment Mortaility
Endemic Location- inadequate water treatment
Transmission - humans and brackish water - fecal/oral
Incubation- hours to 5 days
Important S/S - profuse rice water D/V
Other s/s - HYPOVOLEMIC SHOCK
Treatment- rehydrate Doxy/Emycin/azithro/cipro
Mortaility - death with hypovolemic shock as soon as 7 hours. FDA- shellfish is a risk
YAWS Endemic Location Transmission Incubation Communicable period Important S/S Other s/s Labs Treatment Mortaility
Endemic Location - poor humid tropics
Transmission- Treponema pallidum/ pertenue
Incubation- 9-90
Communicable period- initial lesion has highest infection rate
Important S/S- limb lesions, non healing papilloma, high bacterial load for 6 pos BONE PAIN
Other s/s- late stages >5yrs disfigurement thickening of palms and soles
Labs- clinical diagnosis
Treatment- cure with one dose of azithromycin or IM PCN
TULAREMIA Endemic Location Transmission Incubation Important S/S Other s/s Labs Treatment Mortaility
Endemic Location- US except Hawaii
Transmission- Fransi. Tularensis RABBITS
Incubation- 3-5 days
Important S/S - fever >104 ulcer glandular=mc, pneumonic is most serious
Labs- culture and serologic test 4x
Treatment- streptomycin x10days, bioterrorism risk
