Palliative care

Question 1

RF for NV

Answer 1

female 
younger agge
anxiety
motion sickness, 
Chemo regimen (combination) and dose (high dose)
previous alcoholic = decreased risk

Question 2

type of treatments causing NV

Answer 2

CHEMO!!
radiaton of abdomen + brain + pelvis
met to brain, bowel obstruction, electolyte imbalance,

Question 3

NV classifications

acute

Answer 3

within min-hours after pts receives treatement due to release of serotonin from GI tract, treatment. 5HT3: ondansetron. aprepitant (both acute and delayed, is an NKI antagonist. steroid: both acute and delayed

Question 4

NV classifications

delayed

Answer 4

after 24 h of treatment.
tx; metoclopramide (do not use longer than 5 days) olanzapine: both are dopamine 2 receptor antagonist. also steroid and aprepitant

Question 5

NV classifications

breakthrough

Answer 5

NV occuring despite patients receiving prophylactic treatment to prevent NV

Question 6

NV classifications

refractory

Answer 6

NV occuring during chemo cycles after prophylactic and/or rescue therapy.

Question 7

Highest risk of NV drugs

Answer 7

Cisplatin! dacarbazine (palliative tx in met melanoma)

cyclophosphamie (high dose)

Question 8

Moderate risk of NV drugs

Answer 8

Carboplatin, low dose cyclophosphamide, doxorubicine and daunorubicin: all of these are used in BREAST CANCER: