Palliative care Flashcards
Half life of immediate release morphine
4hrs
Half life of MST?
12hrs
How much stronger is SC compared to oral morphine?
twice as strong
What are the 4 drugs prescribed in anticipatory care
morphine 2mg
levomepromazine 2.5mg
buscopan 20mg
midazolam 2mg
Signs of opioid toxicity
pin point pupils
hallucinations
myoclonus
renal failure
respiratory distress
Signs of opioid toxicity
pin point pupils
hallucinations
myoclonus
renal failure
respiratory depression
Maximum number of drugs in a syringe driver
3 drugs
Receptors located in the vomiting center
- 5ht
- nk1
- histamine
- muscarinic
receptors located in the vestibular center
- histamine
- musarinic
receptors located in the gi tract for nausea
5ht
higher cortical receptors for nausea
5ht
gaba
receptors located in the chemoreceptor trigger zone
- d2
5ht
nk1
Which receptor does lorazepam work on in nausea?
- GABA
Which receptor does haloperidol work on?
- D2
What receptor does metoclopramide work on?
- D2