Pales, bone Ca cases Flashcards
39 y.o F on birth control and MVI
Ca shows high Ca
otherwise normal CBC and CMP
next step
check PTH
39 y.o F on birth control and MVI Ca shows high Ca otherwise normal CBC and CMP high PTH next step
24 hour urinary Ca
39 y.o F on birth control and MVI Ca shows high Ca otherwise normal CBC and CMP high PTH urine Ca is high
primary hyperPTH
53 y.o F with cc weakness, malaise, constipation and back pain becomes somewhat lethargic normal CXR, low albumin, high Ca normal phosphorus high chloride, high BUN high creatinine next step
Tx Ca
check PTH
53 y.o F with cc weakness, malaise, constipation and back pain becomes somewhat lethargic normal CXR, low albumin, high Ca normal phosphorus high chloride, high BUN high creatinine how Tx the hyper Ca?
loop diuretics- furosemide
IV bisphosphonates– alendronate
53 y.o F with cc weakness, malaise, constipation and back pain becomes somewhat lethargic normal CXR, low albumin, high Ca normal phosphorus high chloride, high BUN high creatinine low PTH next step?
check for malignancy Vit D lab PTHrP bone scan TSH and freeT4 T3 multiple myeloma (SPEP/UPEP) ACE level for sarcoidosis
SPEP UPEP
serum and urine protein electrophoresis
71 y.o F poor appetite weight loss, cramps and weakness PMH crohns \+ trousseaus sign Ca low low next step
albumin
71 y.o F poor appetite weight loss, cramps and weakness
PMH crohns
+ trousseaus sign
Ca low low
low albumin so corrected Ca still a little low
next step
PTH
PO4
Cr
alkaline phosphatase
71 y.o F poor appetite weight loss, cramps and weakness PMH crohns \+ trousseaus sign Ca low low low albumin so corrected Ca still a little low low PO4 normal Cr high alkaline phosphatase high PTH differential?
Vit D problem
71 y.o F poor appetite weight loss, cramps and weakness PMH crohns \+ trousseaus sign Ca low low low albumin so corrected Ca still a little low low PO4 normal Cr high alkaline phosphatase high PTH low 25 hydroxy vit D Dx?
Vit D deficiency
what you expect to see on XR and DEXA of a patient with Vit D deficiency
decreased bone density- osteoporosis
35 y.o F with thyroid cancer
had total thyroidectomy
3 days after surgery had facial cramps
hypoCa
best osteoporosis Tx for women with previous Hx breast cancer
estrogen modulator drugs