Pain Theory Flashcards
Pain
Unpleasant sensory or emotional experiences that is associated with actual or potential tissue damage
Tolerance
A physiological adaptation to a drug that causes a muted drug effect
Opioid-induced hyperalgesia
Pain as a result of exposure to opioids
Hallmark sign
State where there are withdrawal symptoms if drug is not given
Neuromatrix theory of pain
Addresses the influence of sensory, affective, and cognitive aspects of pain
Addresses pain transmission and modulation in certain areas of the brain
Biopsychosocial approach to pain
Views pain as a complex experience affected by sensory input, but also closely influenced by behavioral, cognitive, affective, and environmental factors
Gate Control Theory of Pain
Pain stimuli is either allowed to pass or is blocked by a gate in the dorsal horn of the spinal cord
Anxiety, negative thoughts, poor past experience, or depression can open the gate and increase perception of pain
Positive thoughts and relaxation can close the gate to decrease perceptions of pain
Opioid Mediated Theory of Pain
Theory that endogenous opioids are pain-mediating chemicals that are produced in the body and affect the CNS and PNS
Nociceptors
Receptors that detect and respond to potential or actual tissue damage
Sensitive and responsive to mechanical distorition and variation in chemical components in tissues
Anxiety, stress, or depression may amplify pain perception
A-delta fibers
Myelinated pain fibers that carry sharp, well-localized pain signals
C-fibers
Unmyelinated pain fibers that carry poorly localized burning and aching sensations and are easily injured
Pain pathway
- Afferent fibers
- T-cells receive input from afferent fibers and assist in discriminating the type of pain
- Brain
- Descending inhibitory fibers in higher brain center release neurotransmitters to affect flow of afferent impulses
Somatosensory cortex for pain
Perceives pain as sharp, discriminative, and localized to a specific area
Is responsibile for automatic reactions to pain
Spinoreticulothalamic pathway
Terminates in the thalamus/midbrain region
Perceives pain as diffuse, poorly localized somatic and visceral pain
Frontal cortex in pain
Defines perceptions and response to pain
Signals to release neurotransmitters which moderate and affect flow of afferent impulses