Iontophoresis pharmacology Flashcards
Chemical name
Scientific name that describes its atomic or molecular structure
Generic name
Non-proprietary, abbreviation of chemical name
Trade name
Brand name
Selected by companies selling the drug
Protected by copyright
Pharmokinetics
How the body affects the drug
Concerned with drug’s onset of action, peak concentration level, and duration of action
Includes absorption
Absorption
From time drug is administered until it becomes available for use by the body
Methods
- Passive transport
- Active transport
- Pinocytosis
Passive transport
Requires no cellular energy
Drug moves from area of higher concentration to lower concentration via diffusion
Active transport
Requires cellular energy
Moves drugs from areas of lower concentration to areas of higher concentration
Used to absorb electrolytes such as sodium and potassium
Pinocytosis
Form of active transport
Cells engulf drug particles
Commonly used to transport fat-soluble vitamins
Slow absorption routes
Oral
Intramuscular
Subcutaneous
Faster absorption routes
Increased blood flow
Inhalation
Drug distribution
Process by which drugs are delivered to tissues and fluids of the body
Affected by blood flow, solubility, and protein binding
Protein binding
Drug comes in contact with proteins such as plasma protein albumin
Portion of drug that is bound is inactive and can’t exert a therapeutic effect
Metabolism
Body’s ability to change drug from its dosage form to a more water-soluble form that can then be excreted via enzymes in the liver
Turned into inactive metabolites
Excretion
Elimination of drugs from the body
Peak concentration
Reached when absorption rate equals the elimination rate
