Pain Control & Use of Analgesics in Small Animals Flashcards

1
Q

It is mandatory to treat pain if an animal has…

A

undergone a painful procedure OR has chronic pain requiring treatment of that pain

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2
Q

What is the official definition of pain?

A

“An unpleasant sensory and emotional experience, associated with actual or potential tissue damage or described in terms of such damage”

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3
Q

Pain has an essential protective function to announce…

A

the presence of a potentially harmful stimulus

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4
Q

Pain that has no useful function may be caused by

A

disease, trauma, or surgery and can delay recovery due to stress if left untreated

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5
Q

Appropriate analgesia results in

A
  • a more rapid return to normal function
  • a shorter hospital stay
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6
Q

When you undergo Surgery, you don’t perceive pain; but when you wake up after without appropriate pain meds on board, then…

A

you get excruciating pain when you wake up which is more difficult to treat

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7
Q

We use analgesics in veterinary patients because pain…

A
  • increases distress and suffering
  • increases the stress response
  • increases the metabolic & energy demands
  • increases conditions associated w/ prolonged recumbency
  • self-mutilation
  • ethical obligation for humane care
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8
Q

Studies in humans demonstrate that improperly controlled acute pain can…

A

precipitate a chronic pain syndrome that can be very difficult to control where pain itself becomes the primary disease

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9
Q

Pain assessment is the keystone of

A

pain management

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10
Q

if anything is done to the thorax, there are impacts to … and pain management should be used to facilitate it.

A

Ventilation

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11
Q

For successful treatment of pain, you must…

A

look for & recognise it

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12
Q

pain is now considered the 4th

A

vital sign monitored alongside TPR

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13
Q

Treat…

A

predictable pain

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14
Q

Pain assessment should be performed how often?

A

every 2-4 hours for acute pain

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15
Q

Pain assessment is key to determining

A

the degree & duration of pain treatment BUT should not replace treating predictable pain

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16
Q

Perioperative pain extends for at least… and should be managed accordingly

A

24-72 hours

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17
Q

All invasive procedures, trauma, & medical illnesses cause pain & may leave animals

A

unable to demonstrate pain behaviour

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18
Q

the worse the tissue injury, the worse the pain EXCEPT…

A

neuropathic pain which can be extremely intense despite relatively small tissue injury

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19
Q

Very sick patients may feel pain during

A

routine procedures & nursing

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20
Q

Species, breed, age, illness, temperament, drug admin influence…

A

behavioural responses to pain

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21
Q

compare an animal’s behaviour…

A

before & after the onset of pain if possible…

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22
Q

some animals respond to pain through

A

withdrawal

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23
Q

response to appropriate treatment is the gold standard to measure

A

the presence and degree of pain

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24
Q

always use a validated

A

pain scale, if available

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25
Q

What is the least subjective pain score?

A

composite scales where the observer interacts w/ the animal & assesses its behaviour & physiology

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26
Q

What is the best validated pain scale?

A

Glasgow Vet School Composite Measure Pain Scale (GCMPS)

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27
Q

What are signs of pain in the dog?

A
  • change in posture or body position (hunching/praying position, not resting normal)
  • change in demeanour
  • altered/reduced interaction w/ people (aggression)
  • vocalisations (barking, growling, whining)
  • attention to/guarding affected area
  • reduction in appetite
  • altered mobility (lameness, reluctance to move)
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28
Q

What are the 2 validated pain scales in cats?

A

Glasgow
Botucatu

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29
Q

What things are assessed in the pain scales in cats?

A

posture, demeanour, vocalisations, interactions w/ the observer

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30
Q

The glasgow CMPS-F also addresses

A

facial expression

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31
Q

UNESP-Botucatu MCPS in cats includes

A

BP measurement as an optional variable

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32
Q

The Glasgow CMPS-F is appropriate for assessing

A

medical, surgical, and trauma-associated acute pain

33
Q

UNESP-Botucatu MCPS was validated for

A

pain following OVH

34
Q

When assessing pain in rabbits, what pain score constitutes further pain investigation?

A

Pain score of 2 in any category

35
Q

In rabbits, what categories are used to watch for pain?

A
  • ear shape & position
  • orbital tightening
  • nostril shape
  • cheek flattening
  • whisker change & position
36
Q

When should analgesics be used?

A

Pre-operatively, intra-operatively, and post-op

37
Q

Why do we use pre-op analgesics?

A

to provide pre-emptive analgesia
to facilitate handling/sedate animals

38
Q

Why do we use intra-op analgesics?

A

to reduce response to noxious stimuli
to reduce anaesthetic requirements

39
Q

Why do we use post-op analgesics

A

to control acute pain, reduce distress & suffering, etc
to prevent the development of chronic pain

40
Q

Multimodal analgesia is…

A

the concomitant use of analgesics from separate pharmacological drug groups to provide analgesia by differing modes of action

41
Q

Multimodal analgesia allows for

A
  • better control of intra & post-op pain
  • promotes haemodynamic stability
  • minimises incidence of chronic pain
  • reduces dose & side effects of most drugs
42
Q

How do you build a multimodal analgesic protocol for P’s undergoing surgery?

A
  • Start w/ NSAID, opioid, or both
  • Add local anaesthetic
  • Add CRI
  • Add ancillary techniques
43
Q

Why are local anaesthetics so important?

A

they are the most efficient way of providing analgesia to the area & stop pain stimulus from getting to the brain & will not be perceived upon waking

44
Q

Locals exert action by…

A

blocking action potentials from being propagated along sensory neurons by blocking the sodium channels and preventing depolarisation of the membrane required to trigger an action potential

45
Q

Local anaesthetics completely block

A

the pain pathway from ever generating a response

46
Q

Locals reduce the need for…

A

other intra-operative analgesia

47
Q

What are the main local anaesthetics used?

A

Lidocaine, bupivacaine, ropivacaine

48
Q

What is the main difference between the different types of local anaesthetics?

A

onset & duration of action

49
Q

The speed of onset of action of local anaesthetics depends on…

A

pKa
Near 7.4 = fast onset of action
Higher? = slower onset of action

50
Q

Duration of action of locals depends on…

A

protein binding

51
Q

Potency of local anaesthetics depends on…

A

lipid solubility

52
Q

more lipid solubility in locals =

A

more protein binding

53
Q

What is the onset & duration of effect of lidocaine?

A

Onset of effect: fast
Duration of effect: short

54
Q

What is the onset & duration of effect of bupivicaine?

A

Onset of effect: slow
duration of effect: long

55
Q

What is the onset & duration of effect of ropivacaine?

A

Onset of effect: intermediate
duration of effect: intermediate

56
Q

What are signs of local anaesthetic toxicity?

A

CNS first affected (except bupivicaine)
then CV depression
then death

57
Q

Local anaesthetics should not be given… EXCEPT…

A

IV
Except Lidocaine at slow rate in dogs

58
Q

If using lidocaine spray for intubation, the amount of lidocaine used…

A

needs to be taken into consideration in total lidocaine dosing

59
Q

If you give too much lidocaine during GA, you won’t see signs of toxicity… the patient may just…

A

have a seizure or go into coma

60
Q

What techniques are used with local anaesthetics?

A

Splash block
Tissue infiltration
Intratesticular injection
Bier block (IVRA)
Epidural
Cat sacrococcygeal epidural
Dental blocks
Wound catheters
intra-articular block
specific nerve blocks

61
Q

What is a splash block?

A

Direct topical application of local anaesthetic to incision/wound prior to closure OR during laparotomy

62
Q

What is a tissue infiltration block?

A

Injection of local into SQ tissues around/directly into the incision or wound which blocks the surgery site
Targets nerves: cutaneous nerves of area

63
Q

What is an intratesticular injection?

A

Injection of local into the testicles to desensitise spermatic cord and associated structures and provides analgesia for castration

64
Q

What is a Bier block?

A

Block of the distal limb for a short surgical procedure (<90 mins)

65
Q

What are indications for epidural?

A
  • Sx on hind legs & perineal area
  • Abd & thx procedures
66
Q

What are contraindications for epidural?

A
  • sepsis, bacteraemia
  • Hypovolaemia, hypotension in large animals
  • Pyoderma or neoplastic changes in injection site
  • clotting disorders, thrombocytopaenia
  • abnormal anatomy
67
Q

When do you do a sacrococcygeal epidural in a cat?

A
  • Sx on tail, penis, vulva, or perineal area
  • Dystocia
  • Urethral block
  • Hindlimb & pelvic Sx
68
Q

When are contraindications present with a cat sacrococcygeal epidural?

A

Pyoderma
Anatomical abnormalities/no tail –> Manx cats

69
Q

What are some common problems associated with epidural injection?

A
  • Hypotension
  • Urinary retention
  • Subarachnoid injection
  • Blood in hub of needle (inj off midline)
70
Q

What are rare problems associated with epidural injections?

A
  • Cranial spread of local causing respiratory depression
  • Pruritis
71
Q

What are the uses for a dental block under GA?

A
  • Dental extraction
  • Mandibulectomy & maxillectomy
72
Q

What drugs are used in dental blocks?

A

lidocaine or bupivicaine

73
Q

When doing local dental blocks, what do you have to remember about injecting the medications?

A

you have to divide the volume btw various injection sites which may require diluting the drug

74
Q

Where are dental blocks given?

A
  • infraorbital maxillary block
  • caudal maxillary block
  • rostral mandibular (mental) block
  • caudal mandibular block
75
Q

What other analgesic techniques can be used?

A

CRI, Paracetamol, Gabapentin, Tramadol, Fentanyl Transdermal patches

76
Q

What CRI can be used in dogs for analgesia?

A

morphine, lidocaine, ketamine (MLK)
fentanyl, lidocaine, ketamine (FLK)
or any alone
Medetomidine or dexmedetomidine

77
Q

What CRI are used in cats for analgesia?

A

morphine, ketamine (MK)
fentanyl, ketamine (FK)
or any alone
Medetomidine or dexmedetomidine

78
Q

Paracetamol can only be used in what species of small animals?

A

DOGS

79
Q

what animal cannot receive lidocaine IV?

A

Cats!