Pain assessment and Neuropathic pain Takeda Flashcards
1
Q
Basic 7 of pain assessment
A
Location Quality Quantity Timing Setting Moderating factors Associated symptoms
2
Q
Gabapentin/Pregabalin MOA
A
Block nerve impulse by binding Ca channels.
- Decrease Ca influx into presynaptic nerves
- Decrease release if excitatory neurotransmitters
- Decrease pain nerve firing
3
Q
SNRI treatment of neuropathic pain
A
May use if patient had depression as well
-Block reuptake of NE and%HR
Safer than TCAs
4
Q
TCAs treatment of neuropathic pain
A
Effective to treat continuous burning pain
- Block voltage gated Na channels
- Antagonize NMDA receptors
- ADR: Anticholinergic effects
- Not to be used with cardiac disease of any kind
5
Q
Second-line agents
A
Capsaicin topical
Lidocaine topical
Tramadol 200-400 mg/day
6
Q
Other agents
A
Carbamazepine
Oxcarbazepine
Topiramate
Valproic acid