Pain assessment and Neuropathic pain Takeda Flashcards

1
Q

Basic 7 of pain assessment

A
Location
Quality
Quantity
Timing 
Setting
Moderating factors
Associated symptoms
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2
Q

Gabapentin/Pregabalin MOA

A

Block nerve impulse by binding Ca channels.

  • Decrease Ca influx into presynaptic nerves
  • Decrease release if excitatory neurotransmitters
  • Decrease pain nerve firing
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3
Q

SNRI treatment of neuropathic pain

A

May use if patient had depression as well
-Block reuptake of NE and%HR
Safer than TCAs

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4
Q

TCAs treatment of neuropathic pain

A

Effective to treat continuous burning pain

  • Block voltage gated Na channels
  • Antagonize NMDA receptors
  • ADR: Anticholinergic effects
  • Not to be used with cardiac disease of any kind
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5
Q

Second-line agents

A

Capsaicin topical
Lidocaine topical
Tramadol 200-400 mg/day

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6
Q

Other agents

A

Carbamazepine
Oxcarbazepine
Topiramate
Valproic acid

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