Opioids chronic pain Dole

Question 1

Codeine MME

Answer 1

0.15/1

30 mg morphine/0.15 = 200 mg codeine

Question 2

Morphine MME

Answer 2

1/1

30 mg morphine = 30 mg

Question 3

Hydrocodone MME

Answer 3

1/1

30 mg hydrocodone = 30 mg morphine

Question 4

Oxycodone MME

Answer 4

1.5/1

30 mg morphine/1.5 = 20 mg oxycodone

Question 5

Oxymorphone MME

Answer 5

3/1

30 mg morphine/3 = 10 mg oxymorphone

Question 6

Hydromorphone MME

Answer 6

4/1

30 mg morphine/4 = 7.5 mg hydomorphone

Question 7

CYP2D rapid metabolizers

Answer 7

Need less of the drug due to the metabolite being the active component of the drug

Question 8

Indications for long acting opioids

Answer 8

• Adherence problem
• Patient goes extended time where cannot take SA dose. (sleep, work)
• Question of aberrant behavior
• More than 6 doses/day of opioids