PAIN AS A DRUG TARGET Flashcards
1
Q
What is pain?
A
symptoms, that the patient feels
unpleasant sensory or emotional experience associated with tissue damage
2
Q
What is acute pain?
A
lasting minutes to 3 months, reduces as injury/inflammation heals
3
Q
what is chronic pain?
A
pain lasting >3 months & challenging to treat
4
Q
what is nociceptive?
A
tissue damage/injury (non-neural tissue), pain occurs due to activation of nociceptors
5
Q
somatic pain?
A
sharp, localised, discrete
6
Q
What is visceral (organ) pain?
A
generalised, dull/throbbing/aching pain, hard to pinpoint an area
7
Q
What is neuropathic pain?
A
burning, shooting, numb, tingling (poor prognosis
8
Q
What is the pain pathway?
A
- TRANSDUCTION
- nociceptors translate a noxious stimulus into a nociceptive impulse - TRANSMISSION
- nociceptive impulse transmitted along the spinal cord to brain via dorsal root - MODULATION
- in the Brain, the painful signal is either amplified or dampened - PERCEPTION
- the conscious awareness of the experience of pain (nociception)
9
Q
What is the gate theory of pain?
A
10
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A
11
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A
12
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13
Q
A
14
Q
A
15
Q
A
