CHRONIC PAIN Flashcards

1
Q

what is pain

A

Subjective symptom that causes the patient discomfort
Indicates tissue injury

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2
Q

what is sensory anatomy of pain

A

discriminative, helps localise the site of pain

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3
Q

what is affective anatomy of pain

A

carries information on the degree of pain

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4
Q

what is acute pain

A

Lasting minutes to 3 months
Reduces as injury/inflammation heals

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5
Q

what is cognitive anatomy of pain?

A

thoughtful planning to avoid + prevent further pain

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6
Q

what is chronic pain?

A

Pain lasting >3 months
Challenging to treat
Persistent, long term pain

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7
Q

what is primary chronic pain?

A

has no underlying condition or the pain (or its impact) appears to be out of proportion to any observable injury or disease

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8
Q

what is secondary chronic pain?

A

caused by underlying condition

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9
Q

what is the aetiology of chronic pain

A

Multifactorial problem
Involves the nervous system
Amplification of pain signals
Can be associated with an initial injury or inflammation to tissues, leading to:
Normal response or Abnormal response

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10
Q

what is the demographic risk factors?

A
  • female
  • age over 45
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11
Q

what is the socio-economic risk factors

A
  • socio-economic deprivation
  • unemployment
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12
Q

what are lifestyle risk factors?

A
  • smoking
  • alcohol
  • inactivity
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13
Q

what are clinical risk factors

A
  • multimorbidity
  • obesity
  • comorbid personality disorder
  • psychological distress
  • history of trauma or chronic pain
  • sleep disorder
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14
Q

what are other risk factors

A
  • family history of chronic pain syndromes
  • pregnancy
  • attitudes and beliefs about pain
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15
Q

what are the chronic primary pain examples?

A
  • Chronic widespread pain
  • Complex chronic regional pain syndrome
  • Chronic primary headache & orofacial pain
  • Chronic primary visceral pain
  • Chronic primary musculoskeletal pain
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16
Q

What are the risk factors of chronic widespread pain

A

Female
Middle age
Low household income
Low educational status
Divorced & dramatic life events

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16
Q

what is chronic widespread pain?

A
  • long lasting pain in multiple body regions
  • hypothesised to be caused by aberrant peripheral and central pain processing
  • no clear pathology
  • fibromyalgia
    associated with IBS + chronic headache syndromes
17
Q

what are the associated symptoms with chronic widespread pain?

A

Fatigue
Concentration problems
Psychological distress

18
Q

what is complex regional pain syndrome?

A

case unknown
thought to be result of body reacting abnormally to an injury
resulting in more sever pain which lasts longer than expected

19
Q

what are the clinical features of complex regional pain syndrome?

A

Pain usually only affecting one limb
Allodynia/hyperalgesia
Burning/stabbing/stinging/tingling/numbness
Episodic flare-ups (often linked to stress)
Changes to skin/hair/nail growth in region affected

20
Q

What is biomedical assessment?

A
  • history
  • physical examination
  • investigations
  • previous and current treatment
21
Q

what is psychological assessment?

A
  • assesses mood
  • review psychiatric history, alcohol and illicit drug use, misuse, dependence or addiction, history of physical or sexual abuse
23
Q

what is social assessment?

A
  • ability to self-care
  • occupational performance
  • influence of family on pain behaviour
23
What are the investigations?
- Cancer screening tests - Erythrocyte sedimentation rate (ESR) or C-reactive protein - Full blood count - Thyroid function tests - Ultrasound or magnetic resonance imaging (MRI) scan - X-ray
24
What is the DEPR for managing chronic pain?
- Discuss (goals, priorities) - explain (current evidence, suitable options) - provide (info) - review (options for support)
25
What are the non-pharmacological options?
- supervised group exercise programme - acceptance and commitment therapy - Cognitive behavioural therapy - acupuncture or dry needling
25
What are the benefits of ACT
Improved quality of life & sleep Reduced pain & psychological distress Cost effective
26
What are the benefits of CBT
Psychological treatment Effective in a range of mental health disorders Leads to improvement in quality of life
27
What are the benefits of acupuncture?
Effective in short term Delivered in a community setting Delivered by a band 7 (equivalent or lower) healthcare professional with appropriate training
28
what is an example of a tricyclic antidepressant?
amitriptyline
29
what is the MOA of amitriptyline?
Increases NA & serotonin concentration within the synaptic cleft by inhibiting receptors
30
what is amitriptyline used for
Anxiety disorders, depression, neuropathic pain
31
what are the side effects of amitriptyline?
Anticholinergic syndrome QT prolongation Drowsiness High risk of fatality if taken in overdose
32
What are the examples of Selective serotonin reuptake inhibitors (SSRIs)
Fluoxetine, Sertraline, Citalopram
33
what is the MOA of SSRI
Selectively inhibit the reuptake of serotonin, leading to a high concentration of serotonin in the synaptic cleft
34
What are SSRI's used for?
Anxiety disorders, depression, OCD Full effect may take up to 6 weeks & if effective, should be continued for at least 6 months after recovery
35
What are the potential side effects of SSRI's?
Worsening of anxiety, causing agitation & suicidal ideation (within first 2 weeks) GI upset, including diarrhoea (within first 2 weeks) Sexual dysfunction QTc prolongation Electrolyte imbalance (SIADH)
36
What is an example of
Serotonin & noradrenaline reuptake inhibitors (SNRIs)
37
What is the MOA of SNRI?
Blocks NA & serotonin reuptake leading to high levels of NA & serotonin in the synapse
38
What are SNRI's used for?
anxiety, depression
39
What are the potential side effects of SNRI's?
Worsening of anxiety Hypertension Palpitations Sexual dysfunction Urinary disorders Risk of withdrawal is high