PAIN Flashcards
transduction
convert noxious stimuli to electrical impulses. ex. mechanical (skim knee) thermal (burns) chemical (chemical reaction)
histamine
inflammatory response
lactic acid
nociceptor activation
bradykinin
vasodilator. Important with mediating pain response at the site before the signal gets to the central nervous system.
prostaglandins
send pain stimuli to the CNS
substance P
synthesized receptors to feel pain. Makes nerves more sensitive and quick to respond
serotonin
smooth muscles and promote vasoconstriction
transmission
a- fibers: acute localized pain is sent to the CNS
ex. stub a toe
c- fibers: defuse aching burning type pain
reflex arc: reflex from the pain
perception
Individual interpretation of stimuli.
Increased Sensitivity to Thermal Pain and Reduced Subcutaneous Lidocaine Efficacy in Redheads
threshold
lowest intensity of stimulus that causes recognition of pain
modulation
Regulation or inhibition of pain sensation
neuromodulators
they inhibit the production of pain-transmitting nerves. Both pain and stress activate these modulators. (endogenous opioid compounds)
endorphins
produced at neuro synapsis. Released when things like relaxation techniques are used.
ex. Pain medicine (morphine) through IM injection then IV. causes a distraction which will improve pain response.
enkephalins
less potent and thought to reduce pain by inhibiting substance P. (what our body produces to help manage pain.)
gate control theory
Provides ideas for pain relief emphasizing multiple dimensions of pain and; relationship between pain and emotions. The motor receptor will be accepted first.
ex. sensory, emotional, behavioral, cognitive
cutaneous: superficial
paper cut