PAGET'S DISEASE Flashcards
What age range is Paget’s disease found in ?
Middle aged and elderly population.
What is Paget’s disease ?
Excessive and abnormal remodelling of the bone.
What is Paget’s also known as ?
Osteitis deformans
Where is Paget’s disease most common ?
lumber spine
pelvis
tibia
femur
What are the three phases of Paget’s disease ?
1) OSTEOLYTIC (bone reabsorbed)
2) MIXED SCLEROTIC/LYTIC (new bone being laid down, less organised and random) - Will look irregular and Corser.
3) SCLEROTIC
What are the causes of Paget’s disease ?
Unknown but can be linked to cardiovascular disease.
What are three Paget’s appearance in the skull ?
1Osteoporosis circumscripta.
2 Cotton wool skull
3 Larger skull and widening of the inner and outer plates of the skull.
What are the xray appearance of pagets on a pelvis film?
Osteolysis
Sclerosis
Bone expansion
Loss of diiferentiation of the cortex.
Coarsened trabeculae pattern.
Are there any bloods to look at for Paget’s ?
Levels of ALP in your blood.
In paget’s in the spine what is a classic appearances ?
Picture frame vertebra
Expansion.
How can i tell if its pagets and not mets ?
It will be in one area and wont jump across a joint.