Paeds Flashcards
Transient Tachypnoea of Newborn
Commonest cause of resp distress in newborn period, due to delayed fluid resorption in the lungs, settles in 1-2days
RF - C-section
Inv - CXR (hyperinflation, fluid in horizontal fissure)
-> support, oxygen
Speech and Hearing Milestones
3m - turns to sound
6m - double syllables (adah)
9m - mama, understands no
12m - knows own name
12-15m - 2-6 words (refer at 18m)
2yrs - combine 2 words
2.5yrs - 200 words
3yrs - short sentences, asks what and who, 1-10
4yrs - why, when, how
BLS
Compression: ventilation (30:2 for lay people, 15:2 if two rescuers)
- unresponsive? shout for help
- open airway, feel for breathing
- 5 rescue breaths
- Check circulation (infant use brachial/ femoral, children use femoral)
- 15:2 (compressions = 100-120/min, lower half of sternum in kids or two thumb encircling in infants)
Should be 1/3 of AP chest deep
Greenstick Fracture
Unilateral cortical breach only (not whole way through)
Bowing Fracture
Plastic deformity, without cortical disruption
Infantile colic
Common and benign, normally <3m, cause unknown
= excessive crying, pulling of legs, worse in evening
-> reassurance, gone by 6m, do not use simeticone/ lactase
Croup
URTI, infants and toddlers, parainfluenza
RF - 6m-3yrs, autumn
Inv - clinical, CXR (PA steeple subglottic narrowing, lateral thumb sign)
-> don’t examine throat, single dose PO dex, O2, neb adrenaline in emergency
Admit -
Moderate or severe
<3 months
Known upper airway abnormalities
Uncertain diagnosis (? epiglottitis, quinsy, foreign body)
Severity of Croup
Mild - occasional barking, no stridor, no or mild suprasternal/ IC recession, child is well
Moderate - frequent barking cough, easily heard stridor at rest, wall retraction at rest, no/ little distress, child can be placated
Severe - frequent cough, prominent inspiratory stridor, retraction, sig distress/ agitation/ lethargy/ restless, tachy
GORD
RF - preterm, neuro issues
= <8wks, vom and regurg post-feed, excessive crying while feeding
-> 30 degree head up during feed, sleep on back, small frequent feeds, thickened formula, alginate, PPI (distress, v growth), severe fundoplication
Umbilical Hernia
Most resolve by 3yrs
RF - black, Down’s
Whooping Cough (Pertussis)
Infectious disease, antenatal/ childhood vaccination (not lifelong protection)
Causes - gram-ve bacteria Bordetella pertussis
= 3 phases
1. Catarrhal: 1-2wks, like viral URTI
2. Paroxysmal: 2-8wks, cough gets worse, ^at night/ after feeding, post-cough vom, insp whoop (forced insp against closed glottis), apnoea
3. Convalescent - wks to mths to get better
Inv - nasal swab
-> notifiable, if <21d give PO -mycin, admit <6m, Ab prophylaxis to house
*School excl 48hrs after Abx or 21d from symptom onset
Comp - bronchiectasis, pneumonia, seizures
Cleft Lip and Palate
Most common orofacial congenital deformity, 1 in 1000
RF - polygenic inheritance, maternal anti-epileptic use
= issues with feeding/ speech, otitis media if palate
-> repair cleft lip week 1 to 3m, palate 6-12m
Congenital Diaphragmatic Hernia
Herniation of abdo viscera into chest cavity due to incomplete diaphragm formation, 1 in 2000, 50% mort
80% left-sided posterolateral (Bochdalek)
= pulmonary hypoplasia, resp distress after birth, concave chest, reduced breath sounds, heart sounds displaced medially
Achondroplasia
AD, mutation of fibroblast GFR3, abnormal cartilage
RF - 30% FHx, older parents
= short Limbs (rhizomelia), short fingers (brachydactyly), large head with frontal bossing, narrow foramen magnum, midface hypoplasia (flat nasal bridge), trident hands, lumbar lordosis
Epiglottitis
Rare serious infection, Hib, now more common in adults due to vacc
= rapid onset, fever, generally unwell, stridor, drooling, tripod position
Inv - DO NOT EXAMINE, direct visualisation (senior only), XR (thumb/ steeple sign)
-> ET intubation, oxygen, IV Abx
APGAR
Appearance - pink (2), blue extremities (1), blue all over (0)
Pulse - >100, <100, none
Grimace - cries on stimulation, grimace, none
Activity - active movement, limb flexion, flaccid
Resp - strong/ crying, weak/ irregular, none
Done at 1 and 5mins, repeat at 10 if low
= 0-3 very low, 4-6 moderate, 7-10 good
Appendicitis
RF - 10-20yrs, <4yrs unlikely but present ^perf
= periumbilical pain, radiates to RIF, low fever, minimal vomiting, anorexia, can’t hop on R leg, worse coughing, Rovsing’s
*younger or retrocaecal (psoas) may present atypically
Inv - ^inflam, neut-predominant leucocytosis, US in F, CT
-> lap appendicectomy, prophylactic Abx, lavage if perf
Acute Asthma: Severity
Severe = PEF 33-50%, can’t talk, accessory neck muscles, HR >140 if 1-5yrs or >125 over 5, RR >40 1-5yrs or >30 over 5
Life threatening = O2 <92%, PEF <33%, silent chest, v BP, cyanosis, poor resp effort, exhaustion, confusion
Acute Asthma: Management
BD via spacer (close-fitting mask <3yrs), 1 puff every 30/60secs (up to 10), repeat, refer to hosp
Steroids 3-5days to all with exac;
2-5yrs - 20mg OD
>5yrs - 30-40mg OD
Chronic Asthma management
5-16yrs similar to adults (but if LTRA not helping, stop it)
<5yrs;
- SABA
- 8 week trial of mod ICS - no resolution then review diagnosis, symptoms recur <4 weeks then restart at low dose, if recur >4wks then repeat the trial
- SABA + low ICS + LTRA
- stop LTRA and refer
ADHD
Persistent symptoms of inattention, hyperactivity and impulsivity
RF - 3-7yrs, boys, maybe genetic
= six features 0-16yrs, five in 17yrs+
-> 10 week watch and wait, refer to paeds behavioural CAMHS if not resolved, parental education, drugs last (>5 only) e.g., methylphenidate, lisdexamfetamine
Methylphenidate: monitor weight and height 6mthly, baseline ECG (cardiotoxic)
Autism
Impaired social interaction and communication, stereotyped behaviour/ interests
RF - boys, ADHD and epilepsy
= usually presents before 2-3yrs, any level of intellectual disability (50% impaired), big head circumference: brain vol
-> applied behavioral analysis, preschool program, TEACCH, Denver model, JASPER, family counselling
Benign Rolandic Epilepsy
= 4-12yrs, seizures at night, ^partial (facial paresthesia, strange noises), may have 2nd generalisation
Inv - EEG (centrotemporal spikes)
-> excellent prog, seizures stop in teens
Biliary Atresia
Obliteration or discontinuity in the biliary system
RF - F>M
= neonatal cholestasis in first weeks of life, jaundice, dark urine, pale stools, appetite and growth issues, hepatomegaly
Inv - ^cBR, LFTs, US, excl. ATAT/ CF
-> surgery
Bronchiolitis
Inflammation and infection of the bronchioles, RSV
RF - <1yrs (peaks 3-6m), winter, ^severity if prem/ CHD/ CF
= coryzal, dry cough, SOB, wheeze, fine insp crackles, feeding issues
Immediate ambulance if apnoea, looks unwell to HCP, severe resp distress (grunting, marked recession or RR over 70), central cyanosis or O2 <92%
Consider hospital if RR >60, difficult BF/ oral intake, clinical dehydration
Inv - nasopharyngeal IF
-> humidified oxygen, NG feed, airway suction, Palivizumab to high risk babies
Caput Succadaneum vs Cephaloheamotoma
CS - oedema of the presenting part of the head
= crosses suture lines, resolves in days
CH - bleeding between periosteum and skull (^parietal)
= limited to suture lines, <3 months to heal, jaundice
Cerebral Palsy
Non-progressive lesion of motor pathways in the developing brain
Causes - 80% antenatal (malformation, infection), intrapartum (asphyxia, trauma), postnatal (IV haemorrhage, meningitis, trauma)
Link - learning difficulty, epilepsy, squints, hearing impairment
Spastic: ^tone due to UMN damage, -plegia
Dyskinetic: BG/ SN damage, oro-motor issues or athetoid movements
Ataxic: cerebellar issues
= abnormal tone, delayed motor milestones, abnormal gait, feeding difficulties
Chickenpox
Primary infection with varicella zoster, resp spread, can be caught from someone with shingles
= initial fever, itchy rash on head/ trunk, macular then papular then vesicular
-> school excl until lesions crusted over (≈5 days after rash onset)
Comp - 2nd bacterial (^risk with NSAIDs, group A strep, nec fas)
Measles
RNA paramyxovirus, aerosol spread
= Irritable/ fever/ conjunctivitis prodrome, Koplik spots, rash behind ears to whole body, discrete MP to blotchy confluent, desquamation >1wk, 10% diarrhoea
-> notifiable disease, jab <72hrs if haven’t had it
Comp - OM, pneumonia (^death), encephalitis (1-2wks after), subacute sclerosing panencephalitis (5-10yrs after)
Mumps
RNA paramyxovirus, droplet spread
= fever, muscle pain, parotitis (uni to bilateral)
-> notify
Comp - orchitis, unilateral HL, meningoencephalitis, panc
Rubella
Togavirus, winter and spring
= low fever prodrome, pink MP rash for 3-5days, face to body, suboccipital and postauricular nodes
Comp - arthritis, v PLT, encephalitis, myocarditis, risk of congenital rubella syndrome if contracted during preg
Erythema infectiosum
Fifth disease/ slapped cheek, Parovirus B19, resp spread
= mild fever, rose-red rash on cheeks, may spread (rarely palms and soles), may recur in heat for months
Inv - check maternal IgM and IgG (risk <20wk preg, hydrops fetalis)
-> no school exclusion
Scarlet Fever
Reaction to toxins produced by group A strep (pyogenes), resp droplet spread
= 2-6yrs, <48hr fever, strawberry tongue, pinhead rash, torso (spares palms and soles), circumoral pallor, rough sandpaper texture, desquamation
-> notify, oral pen V for 10d (or azithro), return to school 24hrs after starting Abx
Comp - OM, GN (10d), rheumatic fever (20d)
Hand Foot and Mouth Disease
Coxsackie A16 and enterovirus 71, self-limiting
= sore throat, fever, oral ulcers, later palm/ feet vesicles
-> symptomatic, no school exclusion
Childhood syndromes
Patau (tri 13) - small eyes, cleft, extra fingers
Edwards (tri 18) - small jaw, low ears, overlapping fingers, rocker bottom feet
Fragile X (TNR) - LD, big head, long face, big balls, mitral prolapse
Noonan (12) - webbed neck, excavatum, short, PS
Pierre robin - small jaw, posterior tongue, cleft palate
Prader-Willi (15q) - low tone, small balls, obesity
William’s - short, LD, friendly, neonatal ^Ca, AS
Cri du Chat (5p) - larynx and neuro problems, LD, small head and jaw, wide eyes
Types of CHD
Acyanotic
VSD (Down, Edward, Patau = pansystolic)
ASD
PDA
Coarctation (Turner’s = narrowing at the DA)
AV stenosis
Cyanotic
ToF (1-2m to show)
TGA (most common to present at birth)
Tricuspid atresia
Congenital Infections
CMV - low birth weight, purpura, SN deaf, small head
Rubella - SN deaf, cataracts, glaucoma, CHD (PDA)
Toxoplasmosis - cerebral calcification, chorioretinitis, hydrocephalus
Cows Milk Protein Intolerance/ Allergy
3-6% of children, immediate IgE allergy and delayed intolerance seen, tolerate by 5 or 3yrs
= <3m, formula-fed, regurg, vom, diarrhoea, urticaria, atopic eczema, colic, wheeze, chronic cough, rarely anaphylaxis
Inv - clinical, skin prick/ patch, total and specific IgE (RAST)
-> refer if FTT
Formula fed - extensive hydrolyzed formula, amino acid-based
Breastfed - continue BF but eliminate cows milk from mums diet, use EHF for 6m when stop BF
Neonatal Cyanosis
Very common <24hrs
Inv - nitrogen washout test (non/cardiac cause, Pa02 <15 after 10mins 100% o2 is CHD)
Acrocyanosis: cyanosis around mouth and extremities, immediately after birth for <48hrs
CF
AR, defect in CFTR, ^viscosity of secretions
= meconium ileus, jaundice, recurrent chest infections, steatorrhea, FTT, liver disease, short, DM, delayed puberty, rectal prolapse, nasal polyps, male infertility
Inv - high sweat chloride (>60)
-> BD chest physio, high calorie/fat, avoid other CF patients, vitamin sup, pancreatic enzyme sup, transplant, Lumacaftor for homo delta F508
Comp - colonisation by staph aureus, pseudomonas, burkholderia, aspergillus
DDH
Structural abnormality of the hip, higher chance of subluxation and dislocation, ^left
RF - 6F:M, breech, FHx, 1st child, oligohydramnios, bw >5kg
Inv - screened for at 6-8 week check (Barlow to dislocate posteriorly, Ortolani to relocate), US if 1st degree FHx/ breech 36wk+/ twins, XR >4.5mths
-> Pavlik harness, may need surgery >5m
Management of D and V
-> continue BF, encourage fluids (not fruit juice/ fizzy), if dehydrated give 50ml/kg low osmolarity ORS over 4hrs + maintenance ORS
Causes of Diarrhoea
Gastroenteritis - rotavirus most common (fever, d+v), risk of dehydration and lactose intolerance
Also, cows milk intolerance (most common cause in developed world), toddler diarrhoea, coeliac
Down’s Syndrome
= upslanting palpebral fissures, epicanthic folds, small low ears, Brushfield spots in iris, protruding tongue, flat occiput, single palmar crease, low tone, short, recurrent resp infections
Comp
- bowel: duodenal atresia, Hirschprung’s
- cardiac: endocardial cushion defect (AV septal canal), VSD, secundum ASD, Fallot, PDA
- others incl. subfertility, glue ear, ALL, hypothyroid, atlantoaxial instability, Alzheimers