Extra

Question 1

Oral Allergy Syndrome

Answer 1

IgE-mediated HS to specific raw, plant-based foods, cross-sensitisation

Link - birch pollen, latex allergy

= mild tingling, lip/ tongue pruritis, seasonal variation

Question 2

Allergy Tests

Answer 2

Skin prick - drops of diluted allergen on skin then pierced, wheal if allergic

RAST - blood test, amount of IgE that reacts, graded

Skin patch - for contact dermatitis, allergens on back for 48hrs, read 48hrs later

Question 3

Venom Allergy

Answer 3

-> refer to allergy specialist if reaction to insect bite

Question 4

SVC Obstruction

Answer 4

Oncological emergency, compression of SVC

Cause - small cell lung, lymphoma, breast cancer, aortic aneurysm

= SOB, face/ neck/ arm swelling, headache (worse in morning), visual disturbance, pulseless ^JVP

Question 5

Tumour Markers

Answer 5

mAb
Ca 125 - ovarian
Ca 19-9 - pancreatic
Ca 15-3 - breast

Tumour antigens
PSA - prostate
AFP - HCC, teratoma
CEA - CRC