Paediatrics - Pregnancy and Perinatal Health Flashcards
What are fertility issues linked to
age smoking BMI exercise drugs folate alcohol
What does low levels of folic acid put an unborn child at risk of
spina bifida
Describe the stages of early pregnancy
ovulation happens and then fertilization happens while the oocyte is in the fallopian tube
the embryo/zygote spends first week of life transitioning own the fallopian tube before implanting onto the uterus at approximately day 8 or 9
lots of development has taken place by this stage
once the embryo has implanted there are development changes and beginning of maturity
What are the 3 trimesters
first is 12 weeks
second is 12-28 weeks
third is 28-40 weeks
What are the changes that occur across the diff trimesters
1st - structures of embryos forming and differentiating
2nd - more specialization and further differentiation
3rd - all that happens is growth and changes necessary for successful birth
What are the maternal changes in pregnancy
physical changes hormonal changes hematological changes CV changes coagulation changes
What are the hematological changes
large blood volume produced to protect from death from blood loss at birth
What are the hormonal changes in pregnancy
increased estrogen and progestogen
What does the increased estrogen and progestogen do
act on kidney to increase renin secretion
increased salt and water retention
increased plasma volume by 45%
Why does plasma volume increase
protects against hemorrhage at birth
dilution effect makes Hb fall from 15-12g/dL
How do hormonal changes cause diabetes
reduce insulin sensitivity
Why does the lower esophageal sphincter relax
increase abdominal pressure gives increased GORD
What are the hematological changes in pregnancy
increased production of RC< WC, platelets
20% increase in RC mass
increased platelet consumption makes platelets normal to low
What is the issue with increased WC in pregnancy
increased WC makes diagnosing infection difficult
What are the CV changes
relaxation of vascular smooth muscle
vascular compression by uterus
What is the effect of relaxation of vascular smooth muscle
reduced peripheral resistance
reduced systolic and diastolic BP
compensatory increase in HR by 25%
What is the effect of vascular compression by the uterus
compresses vena cava and aorta
results in difficult with venous return when supine so ensure there is a pillow under one side or sit slightly to the side so no pressure on vessels
What are the coagulation changes in pregnancy
clotting factors production increases
fibrinolysis increases
increased system sensitivity with increased DVT risk
What should pregnant women not eat
raw/slightly cooked meat and raw fish raw eggs non pasteurized milk and milk cheeze spicy grilled and fried food marlin, tuna and shark liver and other entrals and internal organs of a slaughtered animal during the first 3 months
Why should they avoid raw /slightly cooked meat and raw fish
danger of infection with toxoplasmosis
Why should they avoid raw eggs
salmonella