Paediatric Respiratory Flashcards
Differential diagnosis of a wheeze
- Lung parenchyma: pneumonia, pulmonary oedema, enlarged left atrium compressing maintsem bronchi, enlarged hilar lymph node, scoliosis
Asthma
Bronchiolitis
CF
Bronchitis
Aspiration, foreign body inhalation
Causes of inspiratory stridor
Nose and Nasopharynx:
Congenital obstruction
Inflammation: rhinitis, sinusitis
Mouth, oropharynx and hypo pharynx:
1. Tonsillar hypertrophy, masses, foreign body
Larynx:
1. Gastroosesophageal refulx (inflammation
Infection: epiglottis, laryngotracheobronchitis
Masses: haemangiomas, abscess
Trauma: subglottic stenosis, foreign body inhalation
Trachea:
1. Infection: Bacterial Tracheitis
Upper airway diseases that can cause an acute cough
- Common cold: rhinovirus
Parainfluenza, sinusitis, tonsilliti, laryngitis, allergy, vocal cord dysfunction
Lower airway diseases that can cause acute cough
- Asthma
- Infection: Bronchitis due to adenovirus, influenza and parainfluenza
Lung parenchyma disease: empyema, viral and bacterial pneumonia
Upper airway causes of chronic cough
Infection: Chronic sinusitis, tonsilitis, bordatella pertussis
Inflammation: Reflux
Lower airway causes of chronic cough
- Asthma
- Infection
Foreign body - Bronchiectasis
- CF
Psychogenic
Tourette
Abnormal lung mechanics that can cause breathlessness
- Restrictive lung disease: chest wall (obesity), chest deformity, kyphoscoliosis
- Parenchymal lung disease: pneumonia, pulmonary hypertension
- Muscle weakness: Duchenne muscular dystrophy, diaphragmatic paralysis
- Hypoxia: V/Q mismatch in lung disease, pneumonia and pneumothorax
Heart disease: pericarditis and myocarditis
Name three types of lung function testings
Achieved after 5 years old
- FEV1/FVC
- Exercise testing
- Bronchodilator responsiveness
- Pulse oximetry
- ABG
What is the level of Na seen in sweat test to diagnose CF
- Diagnostic: >60 mol/L (suspicious if >40)
What three findings would I find in a person with asthma
- Barrel-shaped chest
- Hyperinflation
- Wheeze and prolongs expiration
What would CXR show for asthma
- Hyperinflation
- Flattened hemi-diapgrams
- Atelectasis (collapse of lung)
Spirometry results for asthma
- PEFR <80% predicted for height
- FEV1/FVC < 80%
- Concave scooped shape in flow volume
- 15% increase in FEV1 when given bronchodilator
Treatment of Inflammation and hyperactivity in asthma
- Beclometasone (inhaled steroid)
- Prednisolone
- Methylxanthines: theophylline
- Leukotriene inhibitor: montelukast
Side effects of steroid treatment in asthma
- Impaired growth
- Oral candidiasis
- Altered bone metabolism
- Adrenal suppression
Side effects of theophylline
- Vomiting
- Headaches
- Arrythmias
How are acute infrequent asthmatic episodes managed
EITHER B2 bronchodilators or short-douse red and nebuliser bronchodilator in more severe episodes
How are frequent asthmatic episodes treated
- B2 and low dose inhaled steroid
What defines frequent episodic asthma
- Every 2-4 weeks
What defines persistent asthma
- > 3 episodes/week, with cough at night and morning
Management of persistent asthma
- Long acting b2
- Oral steroids
- Oral montelukast
- Use prophylactically inhaled steroids
Management of exercise induced asthma
- Use b2 bronchodilator before excercise
Stepwise treatment of astjma
- Short acting B2
- Short acting B2 + Low dose steroid inhaled
- Short acting B2 + high dose inhaled steroids
or
Low dose inhaled steroids + long acting bronchodilator - Short acting B2 + High dose steroid + Theophylline
Advice to people with asthma
- Allergen avoidance
- Passive smoking
- Education on inhaler technique
What transmembrane receptor is defected in CF
CFTR
Clinical signs of CF
- Cough and wheeze
- SOB
- Sputum production
- Haemoptysis
- Fatty, pale stools and diarrhoea
- Weight loss or poor weight gain
- Failure to thrive
- Chest infections
Investigations for CF
- Sweat test: cl > 60
- CXR: hyperinfation, increased anteroom-posterior diameter, bronchial dilatation, cysts
- LF: Obstructive pattern with decreased FVC and increased lung volumes
Problems of CF found at infancy
- Meconium ileus
- Neonatal jaundice
- Hypoproteinaemia/oedema
Problems of CF found in childhood
- Recurrent LRTI
- Bronchiectasis
- Poor appetite
- Rectal prolapse
- Sinusistis