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Pharmacology > P450 Inducers and Inhibitors > Flashcards

P450 Inducers and Inhibitors Flashcards

1
Q

CYP1A2

A

inducer: tabacco
inhibitor: cimetidine

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2
Q

CYP2C19

A

inducer: prednisone
inhibitor: ketoconazole

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3
Q

CYP2C9

A

inducer: rifampin
inhibitor: isoniazid

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4
Q

CYP2d6

A

inducer: dexamethasone
inhibitor: cimetidine

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5
Q

CYP2e1

A

inducer: ethanol
inhibitor: watercress

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6
Q

CYP3a4, 5, 7

A

inducer: barbiturates (ex phenobarbital, St John’s Wort)
inhibitor: cimetidine, grapefruit juice

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7
Q

inducers

A

shorter half life, lower efficacy

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8
Q

inhibitors

A

longer half life, higher toxicity

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Pharmacology (6 decks)

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