Oxygenation: Pneumonia Flashcards
Pneumonia
- Acute inflammation of the lung parenchyma
- may be infectious or non-infectious
- was #1 COD in US until antibiotics in use….now #8
- Approx. 50,000 people die yearly
- cost is $20 billion annually
parenchyma
actual oxygen exchange occurs
- alveoli
- brochioles
non-infectious pneumonia
aspiration pneumonia
To get pneumonia…
- microbes are either inhaled or aspirated from oropharynx
- mat also enter via bloodstream
- host defenses overwhelmed
Normal defenses against penumonia
- cough reflex (aspiration pnem)
- pulmonary macrophages
- nasopharyngeal defenses
- cilia lining the respiratory tract
Alveoli and bronchioles invaded…
causing inflammation and immune response
Endotoxins released by microbes…
cause congestion and edema
-associated with gram negative
Bacteria enters lungs through
bloodstream, aspiration of resident bacteria, or person to person via droplet
Bacteria characteristics
- damage cells and usually in one lung
- even distribution of microbes
Streptococcus pneumoniae
most common in community
Staph aureus
healthcare associated
Pneumocystis jiroveci
immunocompromised
mycoplasma pneumoniae
“walking pneumonia”
legionella pneumonphilia
Legionnaires’ disease
Viral Characterisitics
- enter from upper airway and infiltrate alveoli in one or both lungs
- invade cells and kill them, send out debris
- patchy distribution
- influenza and adenovirus
Mycoplasma
does not have cell wall
-neither gram neg or positive…more positive