oxidative phospylation Flashcards
what is OP consist off
ET and atp synthesis
what is OP
where cells utilize oxygen to produce ATP it also involves a series of enzyme-catalyzed reactions that transfer electrons along the electron transport chain
How is energy released converted to ATP?
The chemiosmotic hypothesis – Electron transport and ATP synthesis coupled by a proton gradient
chesmeosmotic hypothesis
synthesis of ATP is driven by a proton gradient across a membrane, typically the inner mitochondrial membrane
OP 1/6
Electrons are transferred from NADH and FADH2, produced during glycolysis and the citric acid cycle, to the electron transport chain located in the inner mitochondrial membrane.
how is the proton graident establoshed in the chesomotic theory?
This proton gradient is established by the pumping of protons across the membrane by complexes in the electron transport chain. As protons flow back across the membrane through ATP synthase, their energy is used to drive the phosphorylation of ADP to ATP
OP 2/6
lectrons move through a series of protein complexes (Complex I, II, III, and IV) in the electron transport chain. As electrons pass through these complexes, energy is released and used to pump protons (H+) from the mitochondrial matrix across the inner mitochondrial membrane into the intermembrane space.
3/6
The pumping of protons establishes a proton gradient across the inner mitochondrial membrane, with a higher concentration of protons in the intermembrane space compared to the mitochondrial matrix.
OP 4/6
Protons flow back into the mitochondrial matrix through ATP synthase, a protein complex embedded in the inner mitochondrial membrane. This flow of protons provides the energy needed to activate ATP synthase.
OP 5/6
ATP synthase utilizes the energy from the proton flow to catalyze the phosphorylation of adenosine diphosphate (ADP) to form adenosine triphosphate (ATP). This process is known as chemiosmotic phosphorylation
OP 6/6
Molecular oxygen (O2) serves as the final electron acceptor in the electron transport chain, combining with electrons and protons to form water (H2O).
what is a proton motive force
protons (h+) pumped out of the matrix
what is the evidence to support the chemisosmotic hypothesis/
A proton gradient can be measured
ATP synthesised if gradient created
how much atp is produced
glycolsis- 2
citric acid cycle- 2
op- 26