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Antibioticos K > Oxazolidinonas > Flashcards

Oxazolidinonas Flashcards

1
Q

Vida media Linezolid

A

5-7 hrs

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2
Q

Excreción Linezolid

A

Se metaboliza por oxidación

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3
Q

RAM Linezolid

A

Dolor abdominal, diarrea y náuseas

Muy infrecuente: erupción cutánea, mielosupresión reversible, cefalea, disgeusia

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4
Q

Interacciones Linezolid

A

Inhibidor no selectivo de la MAO

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5
Q

Administración Linezolid

A

Infusión ev, comprimidos recubiertos y suspensión oral

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6
Q

Bacterias sensibles a Linezolid

A

S.aureus resistente a meticilina
S.pneumoniae resistente a penicilina
Enterococcus resistente a vancomicina
C.difficile

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7
Q

Resistencia a Linezolid

A

Bacterias gram - más habituales no son susceptibles

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8
Q

Mecanismo acción Linezolid

A

Inhibe síntesis proteica al inhibir unión de n-formilmetionil al ribosoma 70s

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Antibioticos K (6 decks)

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