Overview of Pharm Flashcards

1
Q

What are the desired therapeutic effects?

A

prevention, diagnosis, treatment, or cure

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1
Q

Drugs are administered to obtain either _____ OR _____.

A

systemic effects; topical effects

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1
Q

Reactions not at the drug target are _______.

A

idiosyncratic reactions

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2
Q

Route of Administration refers to the ______ of the drug into or on the patient.

A

site of application

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3
Q

What is Cp?

A

plasma concentration

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3
Q

______, whether therapeutic or toxic, are directly correlated to the plasma concentration.

A

Drug effects

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3
Q

What is the volume of distribution?

A

the drug dose for the desired Cp

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4
Q

How much drug reaches the target is called?

A

bioavailability

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5
Q

Drugs do NOT have unique actions in the body; they simply _________.

A

enhance or block the normal physiology of organ systems

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7
Q

the study of the interactions of drugs with biological systems

A

pharmacology

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7
Q

What is the half life?

A

how long the drug remains at the target

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8
Q

Pharmacology

A

the study of the interactions of drugs with biological systems

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9
Q

What is the major organ of metabolism of drugs?

A

the liver

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10
Q

Graphs of ____ determine drug pharmacokinetics.

A

Cp vs time

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12
Q

selection of the right drug in the right dose to interact with the right drug target

A

Pharmacotherapy

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12
Q

What is the MEC?

A

Minimum Effective Concentration

13
Q

Drug target at a non-target system is a ______.

A

side effect

14
Q

Pharmacotherapy

A

selection of the right drug in the right dose to interact with the right drug target

15
Q

How fast the drug reaches the target is called the _____.

A

time to peak

16
Q

Drug effects, whether therapeutic or toxic, are directly correlated to the _____.

A

plasma concentration

18
Q

drug target

A

a membrane or intracellular receptor, an enzyme in a critical biosynthetic pathway, or a membrane transport protein

19
Q

How much of the dose of the drug reaches its target is called __________.

A

bioavailability - F

21
Q

Distribution is defined as the ______ from the _____ to the _____.

A

movement of the drug; bloodstream; tissues

23
Q

Graphs of ____ determine drug pharmacokinetics.

A

Cp vs time

23
Q

______ refers to the elimination of drug activity by the combined processes of metabolism and excretion.

A

Elimination

24
Q

What is the bioavailability?

A

how much drug reaches the target

25
Q

What is the drug dose for the desired Cp called?

A

volume of distribution

26
Q

What is the time to peak?

A

how fast the drug reaches the target

28
Q

How much of the dose of the drug reaches its target is called __________.

A

bioavailability - F

29
Q

2 idiosyncratic reactions are _____ or _____.

A

immunologic; metabolic

30
Q

Drugs are administered to obtain either _____ OR _____.

A

systemic effects; topical effects

31
Q

Absorption is defined as _____ from the site of drug administration into the _____.

A

passage of drug; blood

33
Q

Elimination refers to the elimination of drug activity by the combined processes of _____ and _______.

A

metabolism; excretion

34
Q

What is the major organ of drug excretion?

A

the kidneys

35
Q

How long the drug remains at the target is called?

A

half life

36
Q

Absorption is defined as _____ from the site of drug administration into the _____.

A

passage of drug; blood