Overview of Pharm Flashcards
What are the desired therapeutic effects?
prevention, diagnosis, treatment, or cure
Drugs are administered to obtain either _____ OR _____.
systemic effects; topical effects
Reactions not at the drug target are _______.
idiosyncratic reactions
Route of Administration refers to the ______ of the drug into or on the patient.
site of application
What is Cp?
plasma concentration
______, whether therapeutic or toxic, are directly correlated to the plasma concentration.
Drug effects
What is the volume of distribution?
the drug dose for the desired Cp
How much drug reaches the target is called?
bioavailability
Drugs do NOT have unique actions in the body; they simply _________.
enhance or block the normal physiology of organ systems
the study of the interactions of drugs with biological systems
pharmacology
What is the half life?
how long the drug remains at the target
Pharmacology
the study of the interactions of drugs with biological systems
What is the major organ of metabolism of drugs?
the liver
Graphs of ____ determine drug pharmacokinetics.
Cp vs time
selection of the right drug in the right dose to interact with the right drug target
Pharmacotherapy
What is the MEC?
Minimum Effective Concentration
Drug target at a non-target system is a ______.
side effect
Pharmacotherapy
selection of the right drug in the right dose to interact with the right drug target
How fast the drug reaches the target is called the _____.
time to peak
Drug effects, whether therapeutic or toxic, are directly correlated to the _____.
plasma concentration
drug target
a membrane or intracellular receptor, an enzyme in a critical biosynthetic pathway, or a membrane transport protein
How much of the dose of the drug reaches its target is called __________.
bioavailability - F
Distribution is defined as the ______ from the _____ to the _____.
movement of the drug; bloodstream; tissues
Graphs of ____ determine drug pharmacokinetics.
Cp vs time
