Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immunology > Overview of Immunology > Flashcards

Overview of Immunology Flashcards

1
Q

innate immune system

A

noncellular and cellular processes that hold down an infection until acquired is generated, first line of defense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

acquried immune system

A

clears infection with high specificity and efficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

PRR

A

receptors on innate cells, recognize PAMPs on pathogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

primary lymphoid tissues

A

bone marrow

thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

bone marrow

A

all precursor cells generated for immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

thymus

A

where T cells mature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

hematopoietic stem cell differentiates into

A

common lymphoid progenitor
common myeloid progenitor
common erythroid megakaryocyte progenitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

common lymphoid progenitor differentiates into

A

B cell

NK/T cell progenitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

NK/T cell progenitor differentiates into

A

NK cell

effector T cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

B cell differentiates into

A

plasma cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

common myeloid progenitor differentiates into

A

common granulocyte progenitor

unknown progenitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

common granulocyte progenitor differentiates into

A

neutrophil
basophil
eosinophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

unknown progenitor differentiates into

A

monocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

monocyte differentiates into

A

dendritic cell, macrophage, mast cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

common erythroid megakaryocyte progenitor differentiates into

A

megakaryocyte

erythroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

megakaryocyte differentiates into

A

platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

erythroblast differentiates into

A

erythrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

erythrocyte function

A

clear immune response from the system

O2 transport

19
Q

megaaryocyte function

A

produce platelets or thrombocytes

20
Q

neutrophil

A

phagocyte of innate immune system
controls bacterial/fungal infections
presence of bands (immature neutrophils) in the system indicate a bacterial infection

21
Q

monocyte

A

precursor to macrophage

22
Q

macrophage

A

phagocyte of innate immune system
control bacterial/fungal infections
activation of T cells-adaptive immune response
express antibody Fc receptors
professional antigen presenting cell
recognize foreign material tagged with opsonins

23
Q

eosinophils

A

innate
granulocyte
control parasitic infections
have IgE receptors

24
Q

basophils

A

innate
granulocyte
not much known about function, thought to be similar to eosinophils

25
Q

mast cells

A 
innate
parasite protection
high affinity IgE receptors on surface
granules contain inflammatory mediators 
hypersensitivity responses
26
Q

mastocytosis

A

patients have an overabundance of mast cells
1. cutaneous-excessive mast cells in skin
2. systemic- excessive mast cells in internal organs and skin
usually early onset is cutaneous then develops into systemic
D816V mutation

27
Q

NK cells

A

innate
controls viral infections
have Fc receptors so can be enlisted in acquired immune response (ADCC)

28
Q

marophage mediated initiation of inflammation

A

PRR recognizes PAMPs which results in production of cytokines and chemokines
important for the innate control of infections

29
Q

spleen

A

secondary lymphoid tissue

storage of new RBCs and removal of old RBCs

30
Q

red pulp

A

site of storage and removal of RBCs

31
Q

periarterial lymphoid sheath

A

T cell zone

32
Q

germinal center

A

B cell zone

33
Q

lympho node

A

secondary lymphoid tissue

34
Q

lymphoid follicle of lymph node

A

B cell zone

35
Q

Peyer’s patches

A

most organized of the GALT

36
Q

antigen presenting cells

A

dendritic cells, macrophages, and B cells

37
Q

most potent APC

A

dendritic cell

38
Q

dendritic cells

A

activate T cells and initiate adaptive immune response

39
Q

2 most important steps in the development of lymphocytes

A
  1. generation of antigen specific receptors

2. removal of determinants with receptors that recognize self

40
Q

B cells

A

produce and secrete antibodies

41
Q

T cells

A

cd4 and cd8 cells

42
Q

cd4 cells

A

cells modulate the activity of other immune cell types through their production of protein signals known as cytokines

43
Q

cd8 cells

A

CD8 effector cells recognize and kill infected host cells

Immunology (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions