overview of hematology Flashcards

1
Q

what are the three types of blood and also the solid portion of the blood?

A

Red Blood Cells (RBCs) / erythrocytes
White Blood Cells (WBCs) / leukocytes
Platelets (PLTs) / thrombocytes

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2
Q

study of blood cells using staining,
counting, analyzing and recording of appearance,
genotype and phenotype of each cell.

A

Hematology

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3
Q

Anucleated, biconcave, discoid cells filled with protein
(hemoglobin)

A

Red blood cells

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4
Q

Transports oxygen and carbon dioxide

A

Red blood cells

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5
Q

loss of oxygen-carrying capacity of blood
▪ reduced RBC count or reduced RBC hemoglobin
concentration

A

Anemia

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6
Q

▪ increased RBC count
▪ increased circulating RBC mass that leads to
hyperviscosity.

A

Polycythemia

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7
Q

_______ matches the osmolality of RBC

A

Normal saline

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8
Q

what is the dilution of RBC

A

1:200

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9
Q

a glass pipette designed for dilution

A

thoma pipette

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10
Q

it is called a glass counting chamber

A

hemacytometer

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11
Q

RBCs are assayed for?

A

Hemoglobin concentration and Hematocrit

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12
Q

HGB measurement relies on what solution?

A

weak solution - potassium cyanide and potassium ferricyanide

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13
Q

potassium cyanide and potassium ferricyanide is called?

A

Drabkin reagent

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14
Q

it is a mixture of whole blood and drabkin reagent

A

cyanmethemoglobin

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15
Q

what is the absorbance of cyanmethemoglobin in spectrometer?

A

540 nm wavelength

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16
Q

alternative for ionic surfactant?

A

sodium lauryl sulfate

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17
Q

ratio of the volume of packed RBCs to the
volume of whole blood.

A

Hematocrit

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18
Q

also called “packed cell volume”

A

hematocrit

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19
Q

light-colored layer between RBCs and
plasma which contains WBCs and platelets

A

buffy coat

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20
Q

volume measurement
recorded in femtoliters (fL). RBC diameter on Wrightstained blood film

A

mean cell volume

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21
Q

grams
per deciliter (g/dL). RBC staining intensity and central
pallor

A

mean cell hemoglobin concentration

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22
Q

variation in diameter or size?

A

anisocytosis

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23
Q

Indicate the ability of bone marrow to increase RBC
production

A

polychromatic erythrocytes

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24
Q

used to differentiate and count young RBCs

A

methylene blue

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25
Q
  • present as protection against infection and injury.
  • produce in bone marrow or lymphoid tissue.
A

white blood cells

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26
Q

what is the dilution of WBC

A

1:20

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27
Q

decrease in WBC

A

Leukopenia

28
Q

increase in WBC

A

Leukocytosis

29
Q

multilobed,
pink- or lavender staining
Engulf and destroy
microorganisms and foreign materials

A

Neutrophils

30
Q

increase in
neutrophils
associated in
bacterial infection

A

Neutrophilia

31
Q

decrease in neutrophils

A

Neutropenia

32
Q

less mature neutrophils

A

Bands

33
Q

Round, bright
orange-red
cytoplasmic
granules and filled with proteins for immune regulation

A

Eosinophils

34
Q

elevated eosinophil
level associated in
allergy or parasitic
infection.

A

Eosinophilia

35
Q

Dark purple,
irregular
cytoplasmic
granules and contains histamines

A

Basophils

36
Q

increased level of
basophils
associated in
hematologic
disease

A

Basophilia

37
Q

provide host immunity
- recognize
antigens, mount
humoral
(antibodies), and
cell-mediated
antagonistic
response

A

Lymphocytes

38
Q

increase in
lymphocytes
associated with
viral infections

A

Lymphocytosis

39
Q
  • decreased level
    associated with
    drug therapy or
    immunodeficiency
A

Lymphocytopenia

40
Q
  • immature
    macrophage
  • most
    abundant cell
    type in body
A

Monocytes

41
Q

increase in
monocytes found
in infections or
inflammation

A

Monocytosis

42
Q

uncontrolled proliferation of clone malignant
WBCS

A

Leukemia

43
Q

– common form of
childhood leukemia.

A

Lymphoblastic leukemia

44
Q

Maintains blood vessel integrity

A

Platelets

45
Q

Adheres to damage blood vessels to form plug and
trigger thrombosis

A

Platelets

46
Q

signal inflammation or trauma

A

Thrombocytosis

47
Q

– rare malignant condition
caused by extremely high platelet count and uncontrolled
platelet production

A

Essential thrombocythemia

48
Q

common consequence of drug
treatment.

A

thrombocytopenia

49
Q

percent distribution of tabulated 100
(or more) WBCs

A

WBC differentials

50
Q

do not flow in bloodstream

A

Endothelial cells

51
Q

the liquid clotted portion of blood

A

serum

52
Q

the liquid unclotted portion of the blood

A

plasma

53
Q

transports and nourishes blood cells and provides coagulation enzymes that protects the blood vessel?

A

Plasma

54
Q

what is the least granulocyte in blood composition

A

basophil

55
Q

what is the most abundant blood composition in children?

A

lymphocyte

56
Q

what is the term called in different shape?

A

poikilocytosis

57
Q

what is the NSS isotomic solution of RBC?

A

0.85%

58
Q

what does the osmality do?

A

it gives balance to the blood hence the reason why the NSS of the solution match the osmality

59
Q

how is RBC reported?

A

cells per microliter

60
Q

what is the rbc distribution width?

A

11.5 to 14.5%

61
Q

what is term used for have normal characteristics?

A

normocytic

62
Q

what is the reference interval for the RBC of males?

A

4.20 - 6.00

63
Q

what is the reference interval for the RBC of females?

A

3.80 to 5.20

64
Q

what part of the coagulation is when platelets respond to vascular injury?

A

primary homeostasis

65
Q

what part of coagulation is when the proteins are in the plasma?

A

secondary homeostasis

66
Q

this is the final stage of coagulation and digest clot

A

Fibrinolysis