Overview and intro Flashcards
What is the rate of removal from the body
15 mg/100ml/hr
what is ethanol turned into by alcohol dehydrogenase?
Acetaldehyde
What is acetaldehyde turned into by Acetaldehyde dehydrogenase
Acetate
What is the compound responsible for hangovers
Acetaldehyde
where does most of the absorption take place
small intestine
where does 20% of absorption take place
stomach
What are the different levels of alcohols and what do they mean?
<100: fun
100-200: wide emotions and blurry
>200: fucked
What is alcoholic ketoacidosis?
XS NADH, usually associated with those who are malnourished
What is used in Antabuse?
acetaldehyde
What is methanol broken down into?
Formaldehyde and then formic acid
how do you treat methanol poisoning?
alcohol and dialysis
Why is there is limited metabolism?
due to limited alcohol dehydrogenase
What speeds up gastric emptying?
antihistamines and metoclopramide
Are aerated drinks absorbed faster or slower?
Faster
how do you ‘cure’ a hangover?
inhibit prostaglandins and increase metabolism
What do south east Asians have?
a variant ineffective variant of aldehyde dehydrogenase
What percentage of alcohol is metabolised in the liver?
90%
How do you increase tolerance?
upregulating alcohol dehydrogenase
What happens when ethanol stimulates the cerebellum
Speech and co-ordination
What happens when ethanol stimulates the cortex
talkative
What happens when ethanol stimulates the limbic system
memory loss
What happens when ethanol stimulates the reticular formation
consciousness
What happens when ethanol stimulates the lower brain stem
breathing and blood pressure