Overview and intro Flashcards

1
Q

What is the rate of removal from the body

A

15 mg/100ml/hr

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2
Q

what is ethanol turned into by alcohol dehydrogenase?

A

Acetaldehyde

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3
Q

What is acetaldehyde turned into by Acetaldehyde dehydrogenase

A

Acetate

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4
Q

What is the compound responsible for hangovers

A

Acetaldehyde

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5
Q

where does most of the absorption take place

A

small intestine

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6
Q

where does 20% of absorption take place

A

stomach

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7
Q

What are the different levels of alcohols and what do they mean?

A

<100: fun
100-200: wide emotions and blurry
>200: fucked

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8
Q

What is alcoholic ketoacidosis?

A

XS NADH, usually associated with those who are malnourished

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9
Q

What is used in Antabuse?

A

acetaldehyde

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10
Q

What is methanol broken down into?

A

Formaldehyde and then formic acid

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11
Q

how do you treat methanol poisoning?

A

alcohol and dialysis

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12
Q

Why is there is limited metabolism?

A

due to limited alcohol dehydrogenase

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13
Q

What speeds up gastric emptying?

A

antihistamines and metoclopramide

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14
Q

Are aerated drinks absorbed faster or slower?

A

Faster

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15
Q

how do you ‘cure’ a hangover?

A

inhibit prostaglandins and increase metabolism

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16
Q

What do south east Asians have?

A

a variant ineffective variant of aldehyde dehydrogenase

17
Q

What percentage of alcohol is metabolised in the liver?

A

90%

18
Q

How do you increase tolerance?

A

upregulating alcohol dehydrogenase

19
Q

What happens when ethanol stimulates the cerebellum

A

Speech and co-ordination

20
Q

What happens when ethanol stimulates the cortex

A

talkative

21
Q

What happens when ethanol stimulates the limbic system

A

memory loss

22
Q

What happens when ethanol stimulates the reticular formation

A

consciousness

23
Q

What happens when ethanol stimulates the lower brain stem

A

breathing and blood pressure