Clinicians perspective Flashcards

1
Q

How many deaths world wide did alcohol account for in 2012?

A

5.9%

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2
Q

In the UK what age range and gender is most affected by alcohol related deaths?

A

males between 55-64 years

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3
Q

How many deaths per 100,000 in the UK were related to alcohol?

A

14.2

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4
Q

How much does alcohol cost the NHS?

A

£3.5 bn

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5
Q

How much NHS spending is on alcohol related illness?

A

12%

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6
Q

How much does the drinks industry generate?

A

£11.5 bn

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7
Q

What are the medical consequences related to the ICD-10? (5)

A
  1. withdrawal
  2. Brain/NS effects
  3. CVD
  4. Liver
  5. cancer
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8
Q

How many cancers does alcohol account for?

A

4%

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9
Q

How early can alcohol withdrawal start?

A

6-8 hours from last drink

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10
Q

How long does mild withdrawal last?

A

12- 36 hours

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11
Q

What symptoms occur in mild withdrawal? (5)

A
  • fine tremor
  • sweating
  • anxiety
  • raised heart rate and blood pressure
  • anorexia and nausea
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12
Q

What symptoms occur in moderate withdrawal? (7)

A
  • coarse tremor
  • shaking
  • agitation
  • disorientation
  • confusion
  • seizures
  • hallucinations
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13
Q

How long does moderate withdrawal last?

A

12 hrs - 5 days

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14
Q

How long does severe withdrawal last?

A

12 hrs - 7 days

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15
Q

What symptoms occur in severe withdrawal?

A
  • severe agitation
  • confusion
  • delusions
  • hallucinations
  • circulatory collapse
  • Delirium Tremens
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16
Q

Effects on the NS include (3)…

A

Peripheral neuropathy
Compression neuropathy
myopathy

17
Q

Interactions of alcohol with cardio problems?

A

not a direct link for CVD but a J shaped graph

arrhythmias like holiday heart syndrome and long QT

18
Q

What conditions in the liver are linked with alcohol? (3)

A

cirrhosis
alcohol related steatosis
alcohol related hepatitis

19
Q

What are the key points about alcohol related steatosis? (3)

A

universal in alkies
weird LFTs
reverses with cessation

20
Q

What kind of mortality is associated with alcohol related hepatitis?

A

high

21
Q

what six treatments are used for the liver in alcohol related damage?

A

abstinence, vitamins, nutrition, drugs (beta blockers and rifaximin), TIPPS and transplant

22
Q

What is the drink drive limit?

A

50-80mg per 100ml

23
Q

What four drugs are used in withdrawal?

A

Acamprosate
Naltrexone
Disulphiram
Nalmefene

24
Q

What does Acamprosate used for?

A

used for cravings

25
Q

What is Naltrexone used for?

A

used for desire

26
Q

What is Disulphiram used for?

A

used as aversion therapy

27
Q

What is Nalmefene used for?

A

opioid antagonist