Overdose 2

Question 1

TCAs;
Presentation;
o Sinus ?, ? pupils and urinary ?.
o Progresses into ? and coma.
ABG will show a ? ?.
ECG will show ? ?.
Many will recover with ?  therapy alone.
o IV ? ? if supraventricular / ? tachycardia.

Answer 1

tachy
dilated
retention
drowsiness
met acid
widened qrs
supportive
sodium bicarb
ventricular

Question 2

Benzodiazepines;
Common drug of overdose, but rarely causes severe poisoning.
Presentation;
o Drowsiness, ?, ? and coma.
Management;
o ?;
• ? micrograms over 15 ?.
• Further 100 micrograms at one-? intervals.
• Can induce ?, so monitor for this.

Answer 2

ataxia
dysarthria
flumazenil
200
seconds
minute
fits

Question 3

Opiates;
Presentation;
o ? ?, ? pupils and coma.
Management;
o ? micrograms ? IV.
o If no response after 1 minute, give a further ?micrograms.
o If still no response at 2 minutes, give dose of ?micrograms.
If there is a response, repeat the dose every two ? until ? is adequate.
o ? has a very ? half-life.

Answer 3

resp depression
pinpoint
400
naloxone
800
800
minutes
breathing
naloxone
short

Question 4

Cocaine;
Presentation;
0 ?, tachycardia, hyper?, hyper?, sweating and ?.
ABG shows a ? ?.
There is no specific antidote. Treat with;
0 IV ? for hallucinations/ convulsions.
o Active ? ? for hyperthermia

Answer 4

agitation
thermia
tension
hallucinations
met acid
diazepam
external cooling

Question 5

Salicylates;
Presentation;
0 ?, ?, hyperventilation, ? and sweating.
0 Initially there is a ? ? due to stimulation of the ?centres, yet this develops into a ? ?

Answer 5

tinnitus
vomiting
dehydration
resp alk
resp
met acid

Question 6

Salicylates

Get salicylate levels at 2 ?due to continuing absorption;
o If >?mg/L, consider alkalisation of the ? with ? ? and ? ?.
• Monitor ? as this will also increase K+ excretion.
o If >700mg/L, consider ?.

Answer 6

hours
500
urine
sodium bicarb
pot chloride
ecg
dialysis