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OBGYN > Ovarian Pathology > Flashcards

Ovarian Pathology Flashcards

1
Q

How does the incidence of GYN cancers compare to prognosis?

A

Incidence: Endometrial > Ovarian > Cervical
Prognosis: Ovarian (worst) > Cervical > endometrial

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2
Q

What are the different types of Ovarian cysts?

A 
Follicular 
Corpus luteum
Theca-Lutein
Hemorrhagic 
Dermoid 
Endometroid 
Inflammatory
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3
Q

What are the different types of Malignant ovarian tumors?

A 
Serous Cystadenoma
Mucinous CAD
Granulosa cell tumor 
Immature teratoma
Dysgerminoma
ChorioCA
Yolk sac tumor 
Krukenberg tumor
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4
Q

What are the traits of Follicular cytsts?

A

Most common ov mass in YW
Distention of unruptured graafian follicle
Multiple follicles, usually regress
Insignificant unless secreting estrogen (endometrial hyperplasia)

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5
Q

WHat are the traits of Corpus luteum cyst?

A

Cystic enlargement of corpus luteum w/ central hemorrhage, may rupture -> peritoneal rxn w/ fibrosis and hemmhorage
Regresses spontaneously

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6
Q

What are the traits of Theca-Lutein Cysts?

A

Gonadotropin stim
Ass with: ChorioCA and MOLEs
oft Bilateral
oft multiple

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7
Q

What are the traits of Hemorrhagic Cysts?

A

BV rupture in cyst wall
Cyst grows with inc blood retention
Self resolves

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8
Q

What are the traits of Dermoid Cysts?

A 
Mature Teratome
Germ cell tumor 
MCom 20-30 yo 
Elements from all 3 germ layers
Funct Thyroid tissue 
Pain from ovarian enl and torsion
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9
Q

What are the traits of Endometrioid Cysts?

A

Endometriosis within ovary with cyst formation
Varies w/ mentrual cycle
When filled w/ dark blood, called “chocolate cyst”

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10
Q

What are the traits of Cerous Cystadenoma?

A 
Most common ovarian tumor
60% benign 25% Malignant
Thin walled 
Large, single or multiloculated cystic masses cont serous fluid
lined with fallopian-like epithelium
com Bilateral
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11
Q

What are the most common sources of Ovarian Neoplasms?

A

Surface epithelium 65-70%
Stromal
GC tumor
Mets tumors

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12
Q

What are the traits of Mucinous Cystadenoma?

A

Multiloculated
Unilateral and large
cells linked to cervix
80% benign 10% malignant

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13
Q

What are the traits of Endometrioma?

A

Ectopic Endometrial tissue
Complex mass on US
Pelvic Pain, dysmenorrhea and dysparumia

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14
Q

What are the traits of Brenner Tumor?

A

TRANSITIONAL type epi cells in a dense fibrous stroma
Solid tumor pale yellow/tan
Coffee bean nuclei (also seen in PTC)
Com benign and uni (90%)

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15
Q

What are the charicteristics of Fibromas?

A

Bundles of Spindle shaped fibroblasts
Pulling sensation in groin
Meigs synd: triad of Ovarian fibroma + Ascites + Hydrothorax

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16
Q

What are the traits of Thecomas?

A

Like Granuloma cell tumor may produce estrogen

Presents as an abnormal uterin bleed in PMP woman

17
Q

What are the traits of Serous CystadenoCA?

A 
Most common ovarian malignancy
Freq Bilateral
Psammoma Bodies (also in PTC)
18
Q

WHat is the micro appearance of Serous CystadenoCA?

A

PAPILLARY GROWTH AND HYPERCHROMATIC CELLS

19
Q

What are the traits of Mucinous cystadenoCA?

A

Complex Architecture
Nuclear Atypia
Stromal invasion

20
Q

What is Pseudomyxoma Peritonei?

A

Intraperitoneal accumulation of mucinous material from ovarian or appendiceal tumor

21
Q

What are the traits of immature Teratoma?

A

Aggerssive
Rare, usually solid w/ primitive or embryonic elements (neuroectoderm)
Mature more likely to have thyroid tissue

22
Q

What are the traits of Granulosa cell tumors?

A

Most common sex cord stromal tumor
Often produce estrogen and/or progesterone + abn uterine bleeding, sexual precocity, Br tenderness
Cal-Exner bodies

23
Q

What are cal-Exner bodies?

A

Small eosinphilic fluid filled spaces bet. granulosa cells

24
Q

What are the traits of Dysgerminoma?

A 
Adolescents 
FRIED EGG CELLS
Eq to male Seminoma
Tumor markers: hCG, LDH
Transc Factor: Oct3/4, c-KIT
25
Q

What are the traits of Choriocarcinoma?

A 
Rare
Malignant
Abnormal BHCG
Inc Freq of Theca-lutein cells
CHEMOTHERAPY
26
Q

What are the traits of Yolk sac tumor?

A 
Aggressive
Infants/young children
Schiller-Duval Bodies
AFP Marker
Most common tumor in small infants
27
Q

What are the traits of Krukenberg Tumors?

A

GI malignancy that Mets to the ovaries causing mucin secreting signet cell AdenoCA

OBGYN (18 decks)

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