Ovarian cysts Flashcards
What is the most common type of ovarian cyst?
Follicular cyst
What is a follicular cyst?
Cyst that occurs due to non-rupture of the dominant follicle or failure of atresia in a non-dominant follicle
What is a corpus luteum cyst?
If the corpus luteum does not break down at the end of the menstrual cycle then it may fill with blood/fluid and form a cyst
What is the most common benign ovarian tumour in women <30 years?
Dermoid cyst
What is a dermoid cyst?
- Also called mature cystic teratoma
- Usually lined with epithelial tissue - may contain skin appendages, hair, and teeth
How often are dermoid cysts bilateral?
10-20% of cases
What is the most common type of benign epithelial tumour?
Serous cystadenoma
What is the second most common type of benign epithelial tumour?
Mucinous cystadenoma
Which ovarian mass(es) may cause pseudomyxoma peritonei?
Mucinous cystadenoma
Mucinous cystadenocarcinoma
List the types of ovarian tumours from most to least common.
- Surface derived (epithelial) tumours (65%)
- Germ cell tumours (15-20%)
- Metastatic tumours (Krukenberg - 5%)
- Sex-cord stromal tumours (3-5%)
Describe serous cystadenocarcinomas.
- Malignant epithelial tumour
- Often bilateral
- Psammoma bodies seen (collection of calcium)
Describe mucinous cystadenocarcinomas.
- Malignant epithelial tumour
Describe Brenner tumours.
- Benign epithelial tumour
- Contain Walthard cell rests (benign clusters of epithelial cells)
- Typically have ‘coffee bean’ nuclei
Describe dysgerminomas.
- Most common malignant germ cell tumours
- Similar histological appearance to testicular seminomas
Which condition are dysgerminomas associated with?
Turner’s
Which hormones are secreted by dysgerminomas?
hCG and LDH
Describe yolk sac tumours.
Malignant germ cell tumour
Which hormone is secreted by yolk sac tumours?
AFP
Describe granulosa cell tumours.
The only malignant sex-cord stromal tumour of the ovaries
Which hormone is secreted by granulosa cell tumours? What effect does this have?
- Oestrogen
- Precocious puberty in children
- Endometrial hyperplasia in adults
Describe Sertoli-Leydig cell tumours.
Benign sex cord stromal tumour
Which hormone is secreted by Sertoli-Leydig cell tumours? What effect does this have?
- Testosterone
- Has masculinising effects
Which condition is associated with Sertoli-Leydig cell tumours?
Peutz-Jegher syndrome
Describe fibromas of the ovaries.
Benign sex cord stromal tumour