Ovarian Cancer Flashcards
1
Q
Primary Systemic Therapy Regimens
A
Preferred Regimens
Paclitaxel/carboplatin q3weeks
Paclitaxel/carboplatin/bevacizumab + bev maintenance
Other Recommended Regimens
Paclitaxel weekly/carboplatin weekly
Docetaxel/carboplatin
Carboplatin/liposomal doxorubicin
Paclitaxel weekly/carboplatin q3week
Docetaxel/carboplatin/bevacizumab + bev maintenance
2
Q
PARP maintenance
A
If NO BEV in primary therapy:
BRCA wt: niraparib or rucaparib
BRCA mut: olaparib/niraparib (cat 1) or rucaparib
If BEV in primary therapy:
BRCA wt:
BEV alone or
bev + olaparib (if HRD positive)
BRCA mut:
Bevacizumab + olaparib (cat 1)
Olaparib/niraparib/rucaparib alone
