Ovarian and Endometrial Cancer

Question 1

diagnosis of ovarian cancer

Answer 1

Ca125
TV or TA USS
cytology of pleural fluid or ascites

Question 2

FIGO staging of ovarian cancer

Answer 2

• I = confined to 1 or both ovaries
• II = spread to other pelvic organs e.g. uterus, fallopian tubes
• III = spread beyond pelvis within the abdomen
• IV = spread into other organs e.g. liver and lungs

Question 3

staging system used in ovarian cancer

Answer 3

FIGO staging

Question 4

management of ovarian cancer

Answer 4

surgery
chemotherapy
biological therapy
hormonal manipulation

Question 5

biological options in ovarian cancer

Answer 5

bevacuzimab VEGF

decitabine methylase inhibitor

Question 6

hormone manipulation options in ovarian cancer

Answer 6

tamoxifen
letrozole
for ER +ve

Question 7

RF for endometrial cancer

Answer 7

age
obesity
unopposed oestrogen (HRT, tamoxifen, PCOS, nulliparity, infertility)
precursors

Question 8

management of stage 1 endometrial cancer

Answer 8

TAH + BSO or progesterone

Question 9

management of stage 2 endometrial cancer

Answer 9

radical hysterectomy + adjuvant radiotherapy

Question 10

management of stage 3 and 4a endometrial cancer

Answer 10

radical radiotherapy (EBRT and brachytherapy)

Question 11

management of stage 4b endometrial cancer

Answer 11

palliative

chemo/radiotherapy

Question 12

what age is the HPV vaccine given?

Answer 12

12-13 years old