Lung Cancer Flashcards
how is non-small cell lung cancer classified?
TNM staging
how is small cell lung cancer classified?
limited or extensive (Mountain classification)
investigation options
mediastinoscopy
bronchoscopy
CT-guided biopsy
thoracoscopy
options to quit smoking
nicotine replacement therapy
vareniciline (champix)
nicotine replacement therapy options
gum
patch
nasal spray
inhaler
what is varenicline (champix)
nicotine receptor partial agonist
when is surgery not an option?
stage 3 or 4
poor respiratory reserve
multiple co-morbidities
performance status 3 or 4
surgical options
wedge resection
segmentectomy
lobectomy
pneumonectomy
palliative surgical options
stenting
debulking
what mutation does adenocarcinoma tend to have?
EGFR so can use tyrosine kinase inhibitors
examples of tyrosine kinase inhibitors used in adenocarcinoma
erlotinib
nintedanib
afatanib
ALK translocations in adenocarcinomas management options
crizotinib
certinib
ROS1 translocation
crizotinib
options for squamous cell
nivolumab
crizotinib
