outline of disease process

Question 1

what is the definition of monoclonal?

Answer 1

arising from a single cell

Question 2

what are the 3 causes of cancer development (initiation)

Answer 2

chemical
physical
viral

Question 3

what are the 2 main contributing factors of the promotion stage of cancer?

Answer 3

growth factors

oncogenes

Question 4

what characterises the progression stage of cancer development?

Answer 4

metastasis

Question 5

what are the three stages of cancer development?

Answer 5

initiation
promotion
progession

Question 6

what is autocrine stimulation?

Answer 6

when the cell carries the receptors and secretes the growth factor that causes cancer, cell then escapes normal control mechanisms for growth

Question 7

what is paracrine stimulation?

Answer 7

when the growth factor acting on a cell are produced locally by the cell or its immediate neighbours