Other skin conditions Flashcards
pruritic lesions forming in abdominal striae, 3rd trimester of pregnancy
polymorphic eruption of pregnancy
pruritic blistering lesions beginning in peri-umbilical region before extending to trunk/buttocks/arms 2nd/3rd trimester of pregnancy
pemphigoid gestationis
treatment of pemphigoid gestationis
oral steroids
raised, red, itchy blanching areas that appear, disappear and reappear else where is characteristic of?
urticaria
- lesions last less than <24 hours
treatment of urticaria
non-sedating antihistamine
examples of non-sedating anti-histamines
loratadine
cetirizine
side effects of loratadine/cetirizine
dry mouth
urinary retention
what drug is chlorpheniramine
sedating antihistamine
epistaxis, spider naevi, AV malformations
what condition?
hereditary haemorrhage telangiectasia
- autosomal dominant
itchy papulovesicular rash developed after few days of being in sun
more common in females
polymorphic light eruption
how can polymorphic light eruption be managed
sun protection
desensitisation phototherapy
what type of hypersensitivity is solar urticaria
type 1
features of solar urticaria
immediate onset of symptoms with sunlight exposure
Tx: antihistamines + phototherapy
what is chronic actinic dermatitis
eczema on photo exposed sights
- usually old men
- type 4 hypersensitivity
what is xeroderma pigmentosum
rare, autosomal recessive disorder
rapid photageing of skin + skin cancer - death in teens
drugs that induce photosensitivity
tetracyclines / sulphonamides/ fluoroquinolone thiazide diuretics furosemide NSAIDs amiodarone quinine
what is porphyria cutanea tarda (PCT)
photosensitivity due to deficiency in uroporphyrinogen decarboxylase
features of porphyria cutanea tarda (PCT)
photosensitive rash with blistering and skin fragility on the face and dorsal aspect of hands
hypertrichosis
hyperpigmentation
investigations of PCT
urine - increased uroporphrynogen + pink fluorescence of urine under woods lamp
severe pain/itching/burning on exposure to sunlight and later development of redness + swelling
erythropoietic protoporphyria
what causes erythropoietic protoporphyria
deficiency of enzyme ferrochelatase
what is pityriasis versicolor
hypopigmented scaly patches as a result of fungal proliferation
treatment of pityriasis rosea
topical ketoconazole
single oval plaque on trunk and later progression to widespread red, oval scaly papules
pityriasis rosea
treatment of pityriasis rosea
none - self limiting
