Other skin conditions

Question 1

pruritic lesions forming in abdominal striae, 3rd trimester of pregnancy

Answer 1

polymorphic eruption of pregnancy

Question 2

pruritic blistering lesions beginning in peri-umbilical region before extending to trunk/buttocks/arms 2nd/3rd trimester of pregnancy

Answer 2

pemphigoid gestationis

Question 3

treatment of pemphigoid gestationis

Answer 3

oral steroids

Question 4

raised, red, itchy blanching areas that appear, disappear and reappear else where is characteristic of?

Answer 4

urticaria

- lesions last less than <24 hours

Question 5

treatment of urticaria

Answer 5

non-sedating antihistamine

Question 6

examples of non-sedating anti-histamines

Answer 6

loratadine

cetirizine

Question 7

side effects of loratadine/cetirizine

Answer 7

dry mouth

urinary retention

Question 8

what drug is chlorpheniramine

Answer 8

sedating antihistamine

Question 9

epistaxis, spider naevi, AV malformations

what condition?

Answer 9

hereditary haemorrhage telangiectasia

- autosomal dominant

Question 10

itchy papulovesicular rash developed after few days of being in sun
more common in females

Answer 10

polymorphic light eruption

Question 11

how can polymorphic light eruption be managed

Answer 11

sun protection

desensitisation phototherapy

Question 12

what type of hypersensitivity is solar urticaria

Answer 12

type 1

Question 13

features of solar urticaria

Answer 13

immediate onset of symptoms with sunlight exposure

Tx: antihistamines + phototherapy

Question 14

what is chronic actinic dermatitis

Answer 14

eczema on photo exposed sights

• usually old men
• type 4 hypersensitivity

Question 15

what is xeroderma pigmentosum

Answer 15

rare, autosomal recessive disorder

rapid photageing of skin + skin cancer - death in teens

Question 16

drugs that induce photosensitivity

Answer 16

tetracyclines / sulphonamides/ fluoroquinolone
thiazide diuretics
furosemide 
NSAIDs
amiodarone
quinine

Question 17

what is porphyria cutanea tarda (PCT)

Answer 17

photosensitivity due to deficiency in uroporphyrinogen decarboxylase

Question 18

features of porphyria cutanea tarda (PCT)

Answer 18

photosensitive rash with blistering and skin fragility on the face and dorsal aspect of hands
hypertrichosis
hyperpigmentation

Question 19

investigations of PCT

Answer 19

urine - increased uroporphrynogen + pink fluorescence of urine under woods lamp

Question 20

severe pain/itching/burning on exposure to sunlight and later development of redness + swelling

Answer 20

erythropoietic protoporphyria

Question 21

what causes erythropoietic protoporphyria

Answer 21

deficiency of enzyme ferrochelatase

Question 22

what is pityriasis versicolor

Answer 22

hypopigmented scaly patches as a result of fungal proliferation

Question 23

treatment of pityriasis rosea

Answer 23

topical ketoconazole

Question 24

single oval plaque on trunk and later progression to widespread red, oval scaly papules

Answer 24

pityriasis rosea

Question 25

treatment of pityriasis rosea

Answer 25

none - self limiting