Other Medical Complications of Pregnancy Flashcards

1
Q

What is diagnosis in woman with persistent vomiting, weight loss > 5%, and ketonuria?

A

Hyperemesis gravidarum

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2
Q

What are possible treatments for hyperemesis gravidarum?

A

Phenergan, then reglan, compazine, and tigan

Ginger, vit b12 can help

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3
Q

What is the danger of seizure disorders in pregnancy?

A

Teratogenecity and fetal malformation with antiepileptic drugs

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4
Q

What is management of patients with seizures?

A

Folate prior to conception
Reduce use of anti-epileptic drugs to one drug
Fetal survey at 19-20 weeks
Phenytoin (instead of mgso4) with known seizure disorder rather than preeclampsia

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5
Q

What is the pathophysiology behind eisenmenger syndrome?

A

Initial left to right shunt
Overfilling of right heart = pulmonary HTN and damage
RVH
Right-to-left shunt = chronic hypoxia

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6
Q

Why do patients with aortic stenosis and insufficiency have diminished symptoms during pregnancy?

A

Decreased SVR reduces afterload

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7
Q

Which valvular disease gets worse with pregnancy?

A

Mitral stenosis because inability to meet increased demand

Can lead to CHF

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8
Q

What are patients with marfans treated with?

A

Sedentary lifestyle and beta-blockers

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9
Q

What is perpartum cardiomyopathy?

A

Symptoms of HF and EF

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10
Q

Which clotting factors are increased in pregnancy?

A

All except II, V, and IX

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11
Q

What is the idea behind increased pelvic thrombosis?

A

decreased venous tone due to SMC relaxation with progesterone
Compression of veins by enlarged uterus

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12
Q

What is treatment for DVT and PE?

A

LMWH

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13
Q

Can warfarin be used during pregnancy?

A

NO IT IS TERATOGENIC

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14
Q

What TSH levels are aimed for in pregnancy?

A

Closer to 0.5. Less than 2.5

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15
Q

How should synthroid levels be adjusted during pregnancy?

A

Increased 25-30% because there is more TBG in pregnancy (estrogen)

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16
Q

What are signs of SLE and APL?

A

Symmetric IUGR by 18-20 weeks

Recurrent 2nd trimester pregnancy loss due to placental thrombosis

17
Q

How is SLE and preeclampsia differentiated in pregnancy?`

A

Reduced C3 and C4 in SLE flare

18
Q

What is treatment for SLE flare?

A

High-dose corticosteroids or cyclophosphamide

19
Q

How does SLE affect fetus?

A

Anti-Ro and Anti-La can cross placenta which damage fetal cardiac conduction system = congenital heart blocks

20
Q

What is fetal alcohol syndrome?

A

growth retardation
CNS
abnormal facies
cardiac defects

21
Q

How is alcohol withdrawal managed in pregnancy?

A

Barbiturates instead of benzos which have potential teratogenicity