Diabetes in Pregnancy Flashcards
1
Q
What is the pathophysiology of gestational diabetes?
A
Hormones produced by placenta (HPL) are anti-insulin = insulin resistance
There is beta-cell hypertrophy during first half of pregnancy so signs of GDM don’t arise until second half of pregnancy
2
Q
What are the risks of GDM
A
Fetal macrosomia neonatal hypoglycemia hypocalcemia hyperbilirubinemia polycythemia risk of TIIDM
3
Q
When is GDM screened for?
A
24-28 weeks
4
Q
How is GDM diagnosed?
A
GCT with 50 g glucose, if 1 hour after gluc>130 or 140 then positive
Then GTT - 100 g load glucose and check fasting, and 3 hour glucose (normal = 105/190/165/145
5
Q
What is management of GDM?
A
diet and exercise (limit carbs and overall caloric intake) metformin or glyburide insulin Goals: -Fasting glucose
6
Q
What should mothers with GDM do after delivery?
A
Check for development of T2DM
