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Immune Mechanisms > Other HLAs > Flashcards

Other HLAs Flashcards

1
Q

HLA-E

A

NK cell recognition

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2
Q

HLA-F

A

Localized to ER and Golgi apparatus
Present on trophoblasts in concert with -E and -G
Immune defense of the fetus

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3
Q

HLA-G

A

Fetal derived placental cells
Peptide-bound HLA-G-B2M complex acts on uterine immune cells to promote fetal development while maintaining maternal-fetal tolerance

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4
Q

HLA-H

A

Iron metabolism (think hemachromotosis)

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5
Q

HLA-DM

A

MHCII antigen processing
*does not present Ag peptides and is NOT component of MHCII

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Immune Mechanisms (6 decks)

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