FcR on Leukocytes Flashcards
1
Q
FcgR1
A
IgG
CD64
HIGH
Mo, PMNs, Monos, DC
Phag
2
Q
FcgRIIA
A
IgG
CD32 low
Mo, PMNs, Eos, Platelets
Cell activation, poor phag
3
Q
FcgRIIB1/2
A
IgG
CD32 low
Monos, DCs, Bcell
Feedback inhib of various cell responses
4
Q
FcgRIIC
A
IgG
CD32 low
Mo, PMNs, NK
Cell act, phag
5
Q
FcgIIIA
A
IgG
CD16 low
Mo, NK
ADCC
6
Q
FcgRIIIB
A
IgG
CD16 low
Mo, PMNs Eos
Phag (poor)
7
Q
FceRI
A
IGE
HIGH
mast, basos, Eos
Degranulation, ADCC
8
Q
FceRII
A
IgE
CD23 low
Monos, B cell, DC
Prevent IgE binding to FceRI, inhibit excess IgE levels
9
Q
FcaR
A
IgA
CD89 low
PMNs, Eos, Monos
?cell activation
10
Q
Macrophages
A
All IgG Fc
11
Q
PMNs
A
FcgR: I, IIA, IIC, IIIB
FcaR
12
Q
Monos
A
FcgRI
FceRII
FcaR
13
Q
Dendritic Cells
A
FcgRI, FcgRIIB1/2
FceRII
14
Q
Eosinophils
A
FcgRIIA, FcgRIIIB
FceRI
FcaR
15
Q
Platelet
A
FcgRIIA
