Other DNA Viruses

Question 1

Human
Papilloma Virus
(HPV) morphology/structure

Answer 1

Double
stranded DNA,
no envelope

Question 2

Human
Papilloma Virus
(HPV) modes of transmission

Answer 2

Sexual contact
with an infected
person (even if
assymptomatic).
Can be
transmitted from
mother to child if
infected during
the time of
childbirth.

Question 3

Human
Papilloma Virus
(HPV) virulence factors

Answer 3

Infects and
replicates in
epithelial tissue.
Oncogenic,
blocks p53
tumor supressor
gene

Question 4

Human
Papilloma Virus
(HPV) diseases/symptoms

Answer 4

Genital warts, the most
prevalent STD in the
world. Can lead to
cervical, anal, penile
and throat cancer

Question 5

Human
Papilloma Virus
(HPV) diagnostics

Answer 5

Pap smear can
detect HPV DNA and
abnormal host
cervical cells in
women. Presence of
genital warts for both
men and women.

Question 6

Human
Papilloma Virus
(HPV) prevention/treatment

Answer 6

Protected sexual
intercourse.
Gardasil vaccine
recommended to
prepubescent girls
and boys. Routine
pap smaears for
women. If have
warts, can remove.

Question 7

Human
Papilloma Virus
(HPV) immune response

Answer 7

May be
asymptomatic,
Incurable, once
infected, will
always carry the
virus. Blocks p53
tumor supressor
gene

Question 8

Hepatitis B Virus
(HBV) morphology/structure

Answer 8

Double
stranded DNA,
enveloped
virus
is a
pararetrovirus
(uses reverse
transcription in
the replication
process, but
not a true
retrovirus)

Question 9

Hepatitis B Virus
(HBV) modes of transmission

Answer 9

Exposure to
infectious blood
or body fluids
(e.g., sexual
contact, blood
transfusions,
contaminated
needles, and
tattooing mother
to child during
childbirth)

Question 10

Hepatitis B Virus
(HBV) virulence factors

Answer 10

Infects and
replicates in
hepatocytes

Question 11

Hepatitis B Virus
(HBV) diseases/symptoms

Answer 11

Acute - yellowing of
skin, tiredness and
abdominal pain,
hepatitis (inflammation
of the liver). Chronic -
cirrhosis and liver
cancer. If infected
around the time of
birth often leads to
chronic hepatitis B, if
infected after the age
of five, rarely is
chronic

Question 12

Hepatitis B Virus
(HBV) diagnostics

Answer 12

Detection of viral
antigens or host
antibodies in the
blood

Question 13

Hepatitis B Virus
(HBV) prevention/treatment

Answer 13

Antiviral drugs and
there is a vaccine
given to children
usually within 1st
day of life.

Question 14

Hepatitis B Virus
(HBV) immune response

Answer 14

Hepatocellular
damage and viral
clearance via
cytotoxic T
lymphocytes