Herpes Family of DNA Viruses

Question 1

Herpes Simplex Virus 1 (HSV 1) Morphology/Structure

Answer 1

Double
stranded DNA,
enveloped

Question 2

Herpes Simplex Virus 1 (HSV 1) Modes of transmission

Answer 2

Contact with
infected
person, usually
in early
childhood

Question 3

Herpes Simplex Virus 1 (HSV 1) Virulence Factors

Answer 3

Can show
latency, resides
in the trigeminal
ganglia

Question 4

Herpes Simplex Virus 1 (HSV 1) Diseases/symptoms

Answer 4

Cold sores (blisters)
around mouth
(Herpes labialis) and
gums (Herpetic
Gingivostomatitis)
and less often the
eyes
(Herpetic Keratitis)

Question 5

Herpes Simplex Virus 1 (HSV 1) diagnostics

Answer 5

Painful blisters, can
sometimes be
associated with flulike symptoms.
Blood tests looking
for antibodies to
HSV-1.

Question 6

Herpes Simplex Virus 1 (HSV 1) prevention/treatment

Answer 6

Antiviral drugs
such as aciclovir
and valaciclovir

Question 7

Herpes Simplex Virus 1 (HSV 1) immune response

Answer 7

Interferes with
immune
systems ability to
kill infected cells.
Can show
latency, resides
in the trigeminal
ganglia.

Question 8

Herpes Simplex
Virus 2 (HSV 2) Morphology/structure

Answer 8

Double
stranded DNA,
enveloped

Question 9

Herpes Simplex
Virus 2 (HSV 2) modes of transmission

Answer 9

Sexaual
contact with
infected
person.

Question 10

Herpes Simplex
Virus 2 (HSV 2) virulence factors

Answer 10

Can show
latency, resides
in the sacral
ganglia

Question 11

Herpes Simplex
Virus 2 (HSV 2) diseases/symptoms

Answer 11

Lesions (blisters)
around genital and
anal area

Question 12

Herpes Simplex
Virus 2 (HSV 2) diagnostics

Answer 12

Painful blisters, pain
during urination,
itching. Blood tests
looking for
antibodies to HSV-2

Question 13

Herpes Simplex
Virus 2 (HSV 2) prevention/treatment

Answer 13

Antiviral drugs
such as aciclovir
and valaciclovir

Question 14

Herpes Simplex
Virus 2 (HSV 2) immune response

Answer 14

Interferes with
immune
systems ability to
kill infected cells.
Can show
latency, resides
in the sacral
ganglia.

Question 15

Varicella Zoster
Virus (VZV) morphology/structure

Answer 15

Double
stranded DNA,
enveloped

Question 16

Varicella Zoster
Virus (VZV) modes of transmission

Answer 16

Transmitted by
respiratory
droplets or
contact with
fluid from skin
lesions

Question 17

Varicella Zoster
Virus (VZV) virulence factors

Answer 17

Targets skin
and peripheral
nerves. Can
show latency,
resides in
peripheral
nerves.

Question 18

Varicella Zoster
Virus (VZV) diseases/symptoms

Answer 18

Chicken pox upon
first outbreak - blistery
rash that is itchy and
can be painful.
Although chicken pox
is usually mild, can
develop encephalitis
or pneumonia. Can
reoccur later as
shingles.

Question 19

Varicella Zoster
Virus (VZV) diagnostics

Answer 19

Visible blistery rash,
can also diagnose
via DNA analysis of
blister fluid.

Question 20

Varicella Zoster
Virus (VZV) prevention/treatment

Answer 20

Routine vaccine
given to children.
Antiviral drugs
such as aciclovir
for chicken pox
and valaciclovir for
shingles.

Question 21

Varicella Zoster
Virus (VZV) immune response

Answer 21

Interferes with
immune
systems ability to
kill infected cells.