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Pharma > Other Cell Wall synthesis inhibitors > Flashcards

Other Cell Wall synthesis inhibitors Flashcards

1
Q

Monobactams

A 
Aztreonam 
Resistant to b-lactamase 
Binds to PBP3
Activity towards gram negative aerobes 
IV ; eliminated renally 
Synergistic with aminoglycosides
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2
Q

Carbapenem

A

Imipenem
Low susceptibility to b - lactamase
Gram negative rode , positive cocci , anaerobes
Enterobacter infections
Metabolized renally ; combined with cilastatin to block degradation

Cross allergenicity with penicillins

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