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Pharma > Antimicrobial drugs > Flashcards

Antimicrobial drugs Flashcards

1
Q

Cell wall synthesis inhibitors

A 
Penicillins 
Cephalosporins 
Vancomycin 
Cycloserine 
Bacitracin 
Azoles
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2
Q

Cell membrane permeability

A

Polymixins ( detergent )
Nystatin ( antifungal )
Amphotericin B ( Antifungal )

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3
Q

Protein synthesis inhibitors

A 
Bacteriostatic : 30S or 50s ribosome function interference 
Cholramphenicol
Tetracyclines
Macrolides 
Lincosamides

Bactericidal : 30S ribosome subunit
Aminoglycosides

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4
Q

Nucleic acid synthesis interference

A

Rifamycin : Inhibit DNA dependent rna polymerase

Fluroquinolones : inhibit DNA gyrase

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5
Q

Antimetabolites

A

Sulfonamides

Trimethoprim

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6
Q

Antivirals

A

Zidovudine

Acyclovir

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7
Q

Beta lactam antibiotics

A

Penicillin
Cephalosporins
Carbapenems
Monobactams

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8
Q

Penicillinase or beta lactamase resistant penicillins

A 
Methicillin 
Nafcillin 
Oxacillin 
Cloxacillin 
Dicloxacillin 
Fluxacillin
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9
Q

Extended spectrum penicillins

A

Aminopenicillins
Carboxypencillins
Ureidopenicillins

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10
Q

Ampicillin

A

Gram positive listeria monocytogenes

Enterpcoccal species

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11
Q

Amoxicillin

A

Better oral absorption than ampicillin
Less drug remaining in GI tract
Prophylactic agent by dentists for ; Prevention of bacterial endocarditis

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12
Q

Carboxypencillins

A

Ticarcillin

Gram negative bacilli ; pseudomonas aerugionsa

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13
Q

Ureidopenicillin

A

Piperacillin

Gram negative bacilli ; pseudomonas aeruginosa
Klebsiella pneumonia

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