Other Flashcards
Eosinophilic oesophagitis Gastritis
What is eosinophilic oesophagitis?
Chronic immune/allergen mediated condition
Clinical definition of eosinophilic oesophagitis?
Symptoms of oesophageal dysfunction
Pathological definition of eosinophilic oesophagitis?
Eosinophilic infiltration of the oesophageal epithelium in absence of secondary causes of local or systemic eosinophilia.
Signs & symptoms of eosinophilic oesophagitis?
Food bolus obstruction Dysphagia Impaction (food stuck after swallowing) Persistent heartburn Regurgitation Upper abdominal pain
Investigations of eosinophilic oesophagitis?
Upper endoscopy
Biopsy
Blood tests
Treatment of eosinophilic oesophagitis?
Topical/swallowed corticosteroids
Dietary elimination
Endoscopic dilatation
What is gastritis?
Inflammation in the gastric mucosa
What are the 3 causes of gastritis?
Autoimmune
Bacterial
Chemical injury
Describe autoimmune gastritis & its complication
Autoantibodies to parietal cells & intrinsic factor
Decreased acid secretion & loss of intrinsic factor
What is associated with loss of intrinsic factor
Vitamin B12 Deficiency
What bacteria causes bacterial gastritis?
H.pylori
What causes chemical gastritis? (3)
Drugs (NSAIDs)
Alcohol
Bile reflux
Commonest cause of gastritis
Bacterial - H.pylori
Investigations for gastritis (4)
Upper endoscopy (clinical features seen)
Biopsy
Blood tests (RBC)
Stool test
Symptoms of gastritis (10)
Nausea Abdo bloating Abdo pain Vomiting Indigestion Burning or gnawing (between meals or at night) Hiccups Loss of appetite Vomiting of blood or coffee ground Black tarry stool
Treatment of gastritis
H2Blocker (antacid) PPI Vitamin B12 shot Avoiding hot & spicy food Eliminating irritating food (lactose, gluten etc)
What is heartburn?
Retrosternal discomfort or burning
What can heartburn be associated with?
Waterbrash or cough
When patient presents with dysphagia what should be asked about? (4)
Type of food (solid vs liquid)
Pattern (progressive/intermittent)
Associated features (weightloss, regurgitation, cough)
Location (oropharyngeal/oesophageal)
4 types of oesophageal investigations
Endoscopy
Contrast radiology - barium swallow
pH-metry
Manometry
2 types of endoscopy?
Upper GI endoscopy
Oesophago-gastro-duodenoscopy
3 types of pHmetry
Nasal catheter with pH sensors at sphincters
Endoscopic placement
BRAVO pH probe
What is manometry? What does it assess (3)?
Nasal catheter containing multiple pressure sensors
Asses sphincter tonicity, relaxation of sphincters, oesophageal motility