Other Flashcards

Eosinophilic oesophagitis Gastritis

1
Q

What is eosinophilic oesophagitis?

A

Chronic immune/allergen mediated condition

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2
Q

Clinical definition of eosinophilic oesophagitis?

A

Symptoms of oesophageal dysfunction

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3
Q

Pathological definition of eosinophilic oesophagitis?

A

Eosinophilic infiltration of the oesophageal epithelium in absence of secondary causes of local or systemic eosinophilia.

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4
Q

Signs & symptoms of eosinophilic oesophagitis?

A
Food bolus obstruction
Dysphagia
Impaction (food stuck after swallowing)
Persistent heartburn
Regurgitation
Upper abdominal pain
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5
Q

Investigations of eosinophilic oesophagitis?

A

Upper endoscopy
Biopsy
Blood tests

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6
Q

Treatment of eosinophilic oesophagitis?

A

Topical/swallowed corticosteroids
Dietary elimination
Endoscopic dilatation

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7
Q

What is gastritis?

A

Inflammation in the gastric mucosa

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8
Q

What are the 3 causes of gastritis?

A

Autoimmune
Bacterial
Chemical injury

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9
Q

Describe autoimmune gastritis & its complication

A

Autoantibodies to parietal cells & intrinsic factor

Decreased acid secretion & loss of intrinsic factor

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10
Q

What is associated with loss of intrinsic factor

A

Vitamin B12 Deficiency

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11
Q

What bacteria causes bacterial gastritis?

A

H.pylori

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12
Q

What causes chemical gastritis? (3)

A

Drugs (NSAIDs)
Alcohol
Bile reflux

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13
Q

Commonest cause of gastritis

A

Bacterial - H.pylori

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14
Q

Investigations for gastritis (4)

A

Upper endoscopy (clinical features seen)
Biopsy
Blood tests (RBC)
Stool test

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15
Q

Symptoms of gastritis (10)

A
Nausea
Abdo bloating
Abdo pain
Vomiting
Indigestion
Burning or gnawing (between meals or at night)
Hiccups
Loss of appetite
Vomiting of blood or coffee ground
Black tarry stool
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16
Q

Treatment of gastritis

A
H2Blocker (antacid)
PPI
Vitamin B12 shot
Avoiding hot & spicy food
Eliminating irritating food (lactose, gluten etc)
17
Q

What is heartburn?

A

Retrosternal discomfort or burning

18
Q

What can heartburn be associated with?

A

Waterbrash or cough

19
Q

When patient presents with dysphagia what should be asked about? (4)

A

Type of food (solid vs liquid)
Pattern (progressive/intermittent)
Associated features (weightloss, regurgitation, cough)
Location (oropharyngeal/oesophageal)

20
Q

4 types of oesophageal investigations

A

Endoscopy
Contrast radiology - barium swallow
pH-metry
Manometry

21
Q

2 types of endoscopy?

A

Upper GI endoscopy

Oesophago-gastro-duodenoscopy

22
Q

3 types of pHmetry

A

Nasal catheter with pH sensors at sphincters
Endoscopic placement
BRAVO pH probe

23
Q

What is manometry? What does it assess (3)?

A

Nasal catheter containing multiple pressure sensors

Asses sphincter tonicity, relaxation of sphincters, oesophageal motility