Other Flashcards
1
Q
What is paget’ disease?
A
- Focal bone resorption followed by excessive and chaotic bone deposition
- Affects (in order): spine, skull, pelvis and femur
- Serum alkaline phosphatase raised (other parameters normal)
- Abnormal thickened, sclerotic bone on x-rays
- Risk of cardiac failure with >15% bony involvement Small risk of sarcomatous change
2
Q
Management of paget’s
A
Bisphosphonates
