Other Flashcards

1
Q

What does the diaphragm do

A

Closes thoracic outlet
Comprises radial muscle fibres into central tendon
Dimes upward more on the right
Pastures allow things to pass through

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2
Q

What passes through the diaphragm

A

Oesophagus
Aorta
Inferior vena cava

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3
Q

What are the internal intercostal muscles

A

External intercostal
Internal intercostal
Inner most intercostal

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4
Q

What are the venison nerves and artery’s called supplying the intercostal muscles

A

Intercostal nerve artery, vein

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5
Q

How does the thoracic cage move

A

Superior and anterior

Ribs move upward like a bucket Handel

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6
Q

What are the sub decisions of the thoracic cavity

A

Mediastinum (middle of lungs)

Pleural sacks around the lungs

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7
Q

What is the visceral pleura

A

This is the inner membrane surrounding the lungs

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8
Q

What is the parietal pleura

A

This is the outer membrane in contact with the ribs

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9
Q

What lobes does the right king have

A

Superior
Middle
Inferior

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10
Q

What Kobe’s does the left lung have

A

Superior

Inferior

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11
Q

What is the oblique fissure

A

The diagonal one

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12
Q

What is the horizontal fissure

A

This is the fissure in the right lung that separates the superior and middle lobes

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13
Q

What is the HILUM of the lung

A

This is the part of the lung where the bronchi, pulmonary artery, pulmonary veins and pulmonary ligament attach/enter/leave

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14
Q

What is the perimysium

A

Layer around fascicles

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15
Q

What is the epimysium

A

Outer layer of muscle

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16
Q

What is the endomysium

A

Inner layer

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17
Q

What is a fascicles

A

Bundle of muscle cells

18
Q

How are muscles cells formed

A

Myoblasts fusing

19
Q

What are all the different bands in sarcomeres

A

A band length of myosin
I band length actin alone
H zone myosin alone
M like is middle z disk is boundary of sarcomere

20
Q

What does myosin contain

A
Motor domains (heads) 
Have chains
21
Q

What is the bare zone on the myosin strip

A

This is where there are no myosin heads just interlocking heavy chains

22
Q

What is actin made of

A

Globular actin monomers

23
Q

What are the regulatory filaments in muscle contraction

A

Tropomyosin and troponin

24
Q

What happens to expose binding sites

A

Ca binds to troponin causing tropomyosin to move exposing these sites

25
How is the nerve impulse synapsed with muscle
Acetylcholine released | Nicotine’s cholinogeric receptors detect it
26
How are Ca ions released
Transverse tubules DHPR -RyR ca release
27
What is Titin
Keeps myosin filament in place
28
What is a purine
Adenine | Guanine
29
Pyrimidines
C T or U
30
What’s a missence mutation
Change in base so different amino acid
31
What is a nonsense mutation
Base chagrin codon to stop codon and protein is terminated
32
What causes cystic fibrosis
Mutation in chloride ion exporter proteins causing accumulation of mucus
33
What is sickle cell anemia
Abnormalities in haemoglobin and red blood cell shape
34
What is dentinogenesis imperfects
Several forms one caused by C to T mutation
35
What’s a multifactorial genetic disease
Cussed by many genes and environment
36
What does a restriction enzyme do
Cuts at palindromic sequence of 4 bases
37
What’s gel electrophoresis
Separates fragments of DNA | They are sized using markers
38
What’s recombinant DNA tech
Cloning modified DNA
39
What PCR
Amplifying fragments using enzymes and base co raining solutions
40
What’s southern blotting
Nylon membrane used to blot
41
What’s a DNA sequencer
Fluorescent labels to DNA
42
What’s next gen sequencing
Computerised