Other Flashcards
How would you manage a patient who has overdosed/been poisoned?
ABCDE
Supportive care eg airway protection.
Specific management eg gastric lovage, activated charcoal, whole bowel irrigation, urine alkalinisation, dialysis.
Antidotes when indicated eg naloxone, flumazenil, atropine, N-acetylcysteine, glucagon (beta-blocker/calcium channel blockers), digibind.
Follow-up care eg psychiatric services.
What antidote is given to a paracetamol overdose?
Replace glutathione with N-acetylcysteine (parvolex).
What antimetabolite chemotherapy drugs are used in cancer treatment?
Capecitabine.
5-fluorouracil.
6-mercaptopurine.
Methotrexate.
What antibiotic chemotherapy drugs are used in cancer treatment?
Glycopeptide eg Bleomycin.
Enthracycline eg Epirubicin and doxorubicin.
What alkylating/platinating chemotherapy drugs are used in cancer treatment?
Nitrogen mustards eg Cyclophosphamide and Chlorambucil.
Platinating eg Cis-platin.
What microtubule (mitotic spindle) inhibitor chemotherapy drugs are used in cancer treatment?
Vinca alkaloids eg vincristine .
Taxanes.
What chemotherapy can be used to treat oestrogen receptor positive breast cancer?
Selective oestrogen receptor modulator - tamoxifen.
What tyrosine kinase inhibitor (molecular targeting) can be used to treat cancer?
Imatinib.
What is given as premedication before anaesthesia?
Hypnotic-benzodiazepine.
What are the main intravenous anaesthetics used?
Propofol.
Barbiturates.
Ketamine.
What are the main local anaesthetics used?
Bupivacaine.
Ropivacaine.
Procaine.
