Other Flashcards
Type 1 autoimmune hepatitis
+ANA and/or anti-SMA (smooth muscle actin) white females < 40 years old
Type 2 autoimmune hepatitis
anti-LKM1 (liver-kidney microsome type 1) children age 2-14 years old
Type 3 autoimmune hepatitis
anti-SLA/LP (soluble liver antigen/liver pancreas) otherwise same presentation as type 1
platelet alpha granules
thromboglobulin
P-selectin
PDGF
PF4
Platelet fibrinogen
** Missing in Gray platelet synd and Quebec platelet disorder
Thrombospondin
vWF
Platelet delta (dense) granules
ADP (causes vasoconstriction)
ATP
Serotonin
Ca++
** Missing in Wiscott-Aldrich synd, Chediak Higashi synd, and Hermansky-Pudlak synd)
HACEK organisms
blood culture-negative endocarditis
organisms normally found in oral cavity
gram negative bacilli tht grow poorly on normal Gram-negative selective media (fastidious)
Hemophilus aphrophilus
Actinobacilus actinomycetemcomitans
Cardiobacterium hominis
Eikenella corrodens
Kingella kingii
most common pediatric brain tumor
pilocytic astrocytoma
breast carcinomas with good prognosis
tubular
colloid (mucinous)
medullary
papillary
breast carcinomas with bad prognosis
micropapillary
medullary
Good prognostic features in neuroblastoma
Age < 1 year
Differentiation toward ganglia
Low MKI (<100/5000 cells in age 1.5-5; <200/5000 cells in age < 1.5)
Aneuploid (hyperdiploid or near tetraploid)
Bad prognostic features in neuroblastoma
Age > 2 years
Adrenal location
Stage III & IV
Near diploid or tetraploid
N-myc amplification (>10 copies)
Loss of INI-1 staining
rhabdoid tumor
renal medullary carcinoma
epithelioid sarcoma