Other Flashcards

1
Q

Type 1 autoimmune hepatitis

A

+ANA and/or anti-SMA (smooth muscle actin) white females < 40 years old

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2
Q

Type 2 autoimmune hepatitis

A

anti-LKM1 (liver-kidney microsome type 1) children age 2-14 years old

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3
Q

Type 3 autoimmune hepatitis

A

anti-SLA/LP (soluble liver antigen/liver pancreas) otherwise same presentation as type 1

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4
Q

platelet alpha granules

A

thromboglobulin

P-selectin

PDGF

PF4

Platelet fibrinogen

** Missing in Gray platelet synd and Quebec platelet disorder

Thrombospondin

vWF

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5
Q

Platelet delta (dense) granules

A

ADP (causes vasoconstriction)

ATP

Serotonin

Ca++

** Missing in Wiscott-Aldrich synd, Chediak Higashi synd, and Hermansky-Pudlak synd)

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6
Q

HACEK organisms

A

blood culture-negative endocarditis

organisms normally found in oral cavity

gram negative bacilli tht grow poorly on normal Gram-negative selective media (fastidious)

Hemophilus aphrophilus

Actinobacilus actinomycetemcomitans

Cardiobacterium hominis

Eikenella corrodens

Kingella kingii

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7
Q

most common pediatric brain tumor

A

pilocytic astrocytoma

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8
Q

breast carcinomas with good prognosis

A

tubular

colloid (mucinous)

medullary

papillary

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9
Q

breast carcinomas with bad prognosis

A

micropapillary

medullary

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10
Q

Good prognostic features in neuroblastoma

A

Age < 1 year

Differentiation toward ganglia

Low MKI (<100/5000 cells in age 1.5-5; <200/5000 cells in age < 1.5)

Aneuploid (hyperdiploid or near tetraploid)

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11
Q

Bad prognostic features in neuroblastoma

A

Age > 2 years

Adrenal location

Stage III & IV

Near diploid or tetraploid

N-myc amplification (>10 copies)

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12
Q

Loss of INI-1 staining

A

rhabdoid tumor

renal medullary carcinoma

epithelioid sarcoma

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