Osteoporosis

Question 1

WHat is it

Answer 1

most common met. disorder resulting in low bone desity
rate of bone reabsoption more than bone formation
results in frequent fracture

Question 2

Why does it primarily effect people 3

Answer 2

women p menopause (lack of estrogen)
or failyre to develope pek bone mass during childhood
VIT D deficiency

Question 3

Secondary reasons for disease

disease 3 and med

Answer 3

other meds and disease effecr bone metab
celiacs disease hypogonadism
hyperparathroidism steriods long term

Question 4

CLincinal manif of osteopor 5

Answer 4

Fractures first clinical
decrease height c hyphosis (humpback/dowagers hump)
diff bending over
back pain c activities
impaired breathign SOB

Question 5

Risk factors 6

lifestyle diet gender meds

Answer 5

more women vs men
age 60 over
diet decr in CA and VIT D incre in Phosp
lack of weight bearing exercise 
lifestyle- etoh, smoking, cafeeime 
meds - steriods

Question 6

Assessment and Diagn of osteo 5
labs
test

Answer 6

Bone desitometry- bone mineral
DEXA-dual energy xray and absob info on bone at vertebrae hip and wrist
report t score- stanard deciation bone mass den
FRAx- assessment risk by WHO
Lab studies- (wont show until 25-45% )

Question 7

Management of osteo

CA levels

Answer 7

CA- 1000-1300mg
post menopause 1200/1300
over 50 age 800/100 perday
vit D for absb from GI

Question 8

What good for ViT D and CA

Answer 8

sunlight CA
3glasses of skim/ whole vit d enrich
cheeses brocholi

Question 9

MAnagemnt of osteo

Answer 9

weight bearing 20-30 minx 3 days a week improve dalls

Question 10

DIEt for managemtn of osteo7

good sources of CA foods 6

Answer 10

avoid etoh (reab)
canned salmon, milk, brocoli dairy calcium fortified foods cereal OJ

Question 11

Preventign fxr in osteoporosis pts 5

safety

Answer 11

avoid throw rugs, watch step, siderails up, careful ambulation
hip protectors

Question 12

Medications for osteoparosis 5\ types

Answer 12

CA suppl
Biphosphonates 
Caltcitonin
SERMS- select receptor estrogen  
Tetriparatide

Question 13

CA supplemnts meds 3
implem
PC2

Answer 13

caltrate- citracal- oscal-
with vit d beverage- milk
and VIT C beverage to increase absrb
PC- Gi upset moniitor for kid stones

Question 14

whats first line for treatment 3

Answer 14

CA and VIT D suppl and biphosphonates

Question 15

Biphosphonates fxn
meds-4 
teach - 3 
se - 4
PC 2

Answer 15

dronate
Aldendronate, risendronate, ibadronate
yearly infusion of zoledronic 
inhibit oseocyt functn incre bone mass
take c water 20-30 mins a food or med (EMPTY stmc)
have to be active 
sit up 30 mins - 1 hr p taking 
SE- GI- dyspepsia, diarrhea, constip, gassy 
PC- esopheal /ulcers gastric ulcer

Question 16

Calcitonin 3
how give it
se- 4
contrindicated

Answer 16

reduce bone loss turn over- BMD
nasal spray or SQ or IM
Se- nasla irrit (alt nostril), flushing, GI sympt, urinary freq
contraindicated seafood allgery

Question 17

SERMS 
med
contrindica
teach 
PC

Answer 17

PREVENT and TX reduce risk by preserving estrogen w/o effect uterus

raloxifene
COntrindicated - hx of DVT
reinforce monthly self breast
PC- risk for cancer incr estogen

Question 18

Teriparatide

how to give

Answer 18

SQ inj 1 daily (osteoblast build up bone ca)

recombinant PTH